Tag: 289.3312

Sarkar, Mithun et al. published their research in Inorganica Chimica Acta in 2019 | CAS: 1772625-41-8

(S)-4-Benzyl-2-(1,8-naphthyridin-2-yl)-4,5-dihydrooxazole (cas: 1772625-41-8) belongs to naphthyridine derivatives. The naphthyridines have 10 delocalized π-electrons located in five molecular orbitals, each of which is distorted by the presence of the nitrogen atoms causing an electron drift in that direction. Enoxacin, nalidixic acid, and trovafloxacin are 1,8-naphthyridine derivatives with antibacterial properties related to the fluoroquinolones.Application In Synthesis of (S)-4-Benzyl-2-(1,8-naphthyridin-2-yl)-4,5-dihydrooxazole

Chiral 1,8-naphthyridine based ligands: Syntheses and characterization of Di- and tetranuclear copper(I) and silver(I) complexes was written by Sarkar, Mithun;Pandey, Pragati;Bera, Jitendra K.. And the article was included in Inorganica Chimica Acta in 2019.Application In Synthesis of (S)-4-Benzyl-2-(1,8-naphthyridin-2-yl)-4,5-dihydrooxazole This article mentions the following:

Oxazoline and camphor-pyrazole units are introduced on the 1,8-naphthyridine scaffold to access chiral ligands C8H5N2C3H3NOR (R = Ph (L1), CH2Ph (L2)) and L3 (C8H4N2(C11H16N2)2). Metalation of these chiral ligands with Cu(I) and Ag(I) precursors afforded di- and tetranuclear [Cu4I4(L1)2] (1), [Cu4I4(L2)2] (2), [Cu2I2(L3)] (3), [Cu2I(L2)2](OTf) (4), [Ag2(L1)2](OTf)2 (5) and [Ag4(L2)4Br](OTf)3 (6), containing [M4Xn] (n = 1,4 and X = Br, I) or [M2Xn] (n = 0, 1, 2 and X = I) core. All complexes are structurally characterized. Naphthyridine-derived ligands reveal a bridge-chelate coordination motif and hold two metal centers in close proximity. The tetranuclear complexes are dimers of dinuclear complexes bridged by the halides. Electronic absorption and emission spectra of the Cu complexes are reported. Catalytic utilities of all complexes were examined for asym. transformations but they showed poor activity probably due to limited solubility and coordinative saturation at the metal centers. The best results were obtained with [L3/Cu salt] combination for cyclopropanation of styrene, N-H bond insertion and nitroaldol (Henry) reactions with very low enantioselectivity. In the experiment, the researchers used many compounds, for example, (S)-4-Benzyl-2-(1,8-naphthyridin-2-yl)-4,5-dihydrooxazole (cas: 1772625-41-8Application In Synthesis of (S)-4-Benzyl-2-(1,8-naphthyridin-2-yl)-4,5-dihydrooxazole).

(S)-4-Benzyl-2-(1,8-naphthyridin-2-yl)-4,5-dihydrooxazole (cas: 1772625-41-8) belongs to naphthyridine derivatives. The naphthyridines have 10 delocalized π-electrons located in five molecular orbitals, each of which is distorted by the presence of the nitrogen atoms causing an electron drift in that direction. Enoxacin, nalidixic acid, and trovafloxacin are 1,8-naphthyridine derivatives with antibacterial properties related to the fluoroquinolones.Application In Synthesis of (S)-4-Benzyl-2-(1,8-naphthyridin-2-yl)-4,5-dihydrooxazole

Referemce:
1,8-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N2 – PubChem

Ghatak, Tapas et al. published their research in Journal of the American Chemical Society in 2015 | CAS: 1772625-41-8

(S)-4-Benzyl-2-(1,8-naphthyridin-2-yl)-4,5-dihydrooxazole (cas: 1772625-41-8) belongs to naphthyridine derivatives. Heterocyclic nitrogen compounds, including fused 1,5-naphthyridines, have versatile applications in synthetic organic chemistry and play an important role in the field of medicinal chemistry, as many of them have a wide range of biological activities. Transition metal complexes of 1,5-naphthyridine (1,5-napy) seems to form one-dimensional coordination polymers with the ligand acting as bidentate in a “stepped” bridging fashion.Recommanded Product: 1772625-41-8

Olefin Oxygenation by Water on an Iridium Center was written by Ghatak, Tapas;Sarkar, Mithun;Dinda, Shrabani;Dutta, Indranil;Rahaman, S. M. Wahidur;Bera, Jitendra K.. And the article was included in Journal of the American Chemical Society in 2015.Recommanded Product: 1772625-41-8 This article mentions the following:

Oxygenation of 1,5-cyclooctadiene (COD) is achieved on an Ir center using H2O as a reagent. A H-bonding interaction with an unbound N atom of the naphthyridine-based ligand architecture promotes nucleophilic attack of H2O to the metal-bound COD. Irida-oxetane and oxo-irida-allyl compounds are isolated, products which are normally accessed from reactions with H2O2 or O2. DFT studies support a ligand-assisted H2O activation mechanism. In the experiment, the researchers used many compounds, for example, (S)-4-Benzyl-2-(1,8-naphthyridin-2-yl)-4,5-dihydrooxazole (cas: 1772625-41-8Recommanded Product: 1772625-41-8).

(S)-4-Benzyl-2-(1,8-naphthyridin-2-yl)-4,5-dihydrooxazole (cas: 1772625-41-8) belongs to naphthyridine derivatives. Heterocyclic nitrogen compounds, including fused 1,5-naphthyridines, have versatile applications in synthetic organic chemistry and play an important role in the field of medicinal chemistry, as many of them have a wide range of biological activities. Transition metal complexes of 1,5-naphthyridine (1,5-napy) seems to form one-dimensional coordination polymers with the ligand acting as bidentate in a “stepped” bridging fashion.Recommanded Product: 1772625-41-8

Referemce:
1,8-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N2 – PubChem