Continuously updated synthesis method about 65438-97-3

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In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Synthesis of 3,4,6-triaryl-2-pyrones, published in 1977-11-30, which mentions a compound: 65438-97-3, mainly applied to pyrone aryl; pyridinone aryl; selenopheneylpyrone pyridinone; thienylpyrone pyridinone; pyrrolylpyrone pyridinone; selenonium salt diphenyl, Related Products of 65438-97-3.

Reaction of BrCH2COAr with Me2Se gave [Me2Se+CH2COAr] Br-, which with diphenylcyclopropenone gave 80-95% I (Ar = Ph, 2-thienyl, selenophene-2-yl, 1-methylpyrrol-2-yl), which with MeNH2 gave the corresponding II.

If you want to learn more about this compound(2-Bromo-1-(1-methyl-1H-pyrrol-2-yl)ethanone)Related Products of 65438-97-3, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(65438-97-3).

Reference:
1,8-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N2 – PubChem

Discovery of 65438-97-3

Here is a brief introduction to this compound(65438-97-3)Category: naphthyridine, if you want to know about other compounds related to this compound(65438-97-3), you can read my other articles.

The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: 2-Bromo-1-(1-methyl-1H-pyrrol-2-yl)ethanone, is researched, Molecular C7H8BrNO, CAS is 65438-97-3, about 4-Acetylamino-3-(imidazol-1-yl)-benzoic acids as novel inhibitors of influenza sialidase, the main research direction is acetylaminoimidazolylbenzoic acid preparation influenza sialidase inhibitor; imidazolylbenzoic acid preparation influenza sialidase inhibitor; benzoic acid imidazolyl preparation influenza sialidase inhibitor; virucide anti viral agent acetylaminoimidazolylbenzoic acid.Category: naphthyridine.

Two methods for the synthesis of 4-acetylaminobenzoic acids substituted at the 3-position with imidazoles are described. Thus, 4-acetylamino-3-aminobenzoic acid tert-Bu ester was N-alkylated with RCH2COBr (R = Ph, Et, benzofuran-3-yl, etc.) followed by cyclization with cyanamide and hydrolysis to give imidazolylbenzoic acids I (R1 = Ph, furyl, Et, etc.; R2 = NH2). Imidazolylbenzoic acids I (R1 = H; R2 = NH2, H, Et) were prepared by addition of the appropriate imidazole to 3-fluoro-4-nitrobenzoic acid tert-Bu ester followed by reduction of the nitro group, acetylation, and hydrolysis. Many of the compounds are inhibitors of influenza virus sialidases with levels of activity similar to the recently described 4-acetylamino-3-guanidino-benzoic acid (BANA 113).

Here is a brief introduction to this compound(65438-97-3)Category: naphthyridine, if you want to know about other compounds related to this compound(65438-97-3), you can read my other articles.

Reference:
1,8-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N2 – PubChem