Category: 64874-38-0

Application of 64874-38-0, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Article, and a compound is mentioned, 64874-38-0, 6-Bromo-1,8-naphthyridin-2-amine, introducing its new discovery.

Several 2-amino-6-aryl-1,8-naphthyridines were reported. The cyclocondensation of 2,6-diaminopyridine, 2-bromomalonaldehyde in phosphoric acid resulted in the formation of 2-amino-6-bromo-1,8-naphthyridine, which was converted into 2-amino-6-aryl-1,8-naphthyridines by palladium-catalyzed Suzuki reaction with arylboronic acid. It is shown that the Suzuki coupling with palladium catalyst (Pd-132) could be completed efficiently with lower catalyst loading and good to excellent yields. The title compounds were characterized by NMR spectra and mass spectra.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Application of 64874-38-0. In my other articles, you can also check out more blogs about 64874-38-0

Reference£º
1,638-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N632 – PubChem

Reference of 64874-38-0, Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 64874-38-0, molcular formula is C8H6BrN3, introducing its new discovery.

GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED; DEATON, Dave Norman; SHEARER, Barry George; YOUNGMAN, Mark Andrew

A compound of formula (I) wherein R1, R2, R3, R4, X, Y, and A are as defined herein. The compounds of the present invention are inhibitors of hematopoietic prostaglandin D synthase (H-PGDS) and can be useful in the treatment of Duchenne muscular dystrophy. Accordingly, the invention is further directed to pharmaceutical compositions comprising a compound of the invention. The invention is still further directed to methods of inhibiting H-PGDS activity and treatment of disorders associated therewith using a compound of the invention or a pharmaceutical composition comprising a compound of the invention.

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 64874-38-0 is helpful to your research. Reference of 64874-38-0

Reference£º
1,636-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N630 – PubChem

64874-38-0, Name is 6-Bromo-1,8-naphthyridin-2-amine, belongs to naphthyridine compound, is a common compound. 64874-38-0In an article, authors is Bahman Jahromi, Enayatollah, once mentioned the new application about 64874-38-0.

Some new substituted 1,8- naphthyridines 2a, 2b, 2c, 2d, 2e, 2f, 2g have been synthesized by treating various 2-substituted vinamidinium salts 1a, 1b, 1c, 1d, 1e, 1f, 1g with 2,6-diaminopyridine. The structures of the synthesized compounds have been established on the basis of elemental analysis and spectroscopic data (1H-NMR, 13C-NMR, IR, UV/VIS, and mass).

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Reference£º
1,637-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N631 – PubChem