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Changsha Shencheng Biological Technology Co., Ltd.; Bu Gonggaofamingren

The invention discloses a process for preparing 4 – bromo – 1, 8 – two quinolines of the method, in order to 2 – aminopyridine as the starting material, through the ring, brominated, reduction to obtain 4 – bromo – 1, 8 – two quinolines, this compound is an important intermediate of the research and development of new drugs. (by machine translation)

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Nanjing Gentai Pharmaceutical Co., Ltd.; Chen Rongyao; Shen Yu

The present invention relates to a compound of formula I or a pharmaceutically acceptable salt, solvate, hydrate, active metabolite, polymorph, ester, isotopic compound, stereoisomer or prodrug, a pharmaceutical composition comprising a compound of formula I and its use as IDO inhibitor for the preparation of a medicament for preventing or treating cancer, viral infection, depression, cataract, organ transplantation rejection, or autoimmune disease thereof. (by machine translation)

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54569-28-7, Name is 4-Bromo-1,8-naphthyridine, belongs to naphthyridine compound, is a common compound. HPLC of Formula: C8H5BrN2In an article, once mentioned the new application about 54569-28-7.

A number of 1,8-naphthyridines including 8-aza analogues of chloroquine and amodiaquine, and similar 1,8-naphthyridines with 2- and 7-methyl substituents have been prepared.These compounds showed minimal antimalarial activity in a preliminary in vivo screen against Plasmodium vinckei vinckei.

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In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 54569-28-7, name is 4-Bromo-1,8-naphthyridine, introducing its new discovery. Computed Properties of C8H5BrN2

Jiangsu March Optoelectric Technology Co., Ltd.; Zhang Zhaochao; Li Chong

The invention relates to a to pyridine and benzimidazole as the core of the organic compound and its application on the OLED device, compounds of the invention have higher glass transition temperature and molecular thermal stability; and low absorption in the visible light field, high refractive index, when applied to the OLED device after CPL layer, can effectively improve the light extraction efficiency of the OLED device; the compounds of the invention also has deep HOMO energy and high electron mobility, can be used as the OLED device of hole blocking/electron transport layer material, can effectively prevent the hole or energy from the light-emitting layer is transmitted to the electron shell one side, thereby improving the hole and electron in the luminescent layer of the composite efficiency, OLED device to further enhance the light emitting efficiency and service life. (by machine translation)

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FLEXUS BIOSCIENCES, INC.; BECK, Hilary Plake; JAEN, Juan Carlos; OSIPOV, Maksim; POWERS, Jay Patrick; REILLY, Maureen Kay; SHUNATONA, Hunter Paul; WALKER, James Ross; ZIBINSKY, Mikhail; BALOG, James Aaron; WILLIAMS, David K; MARKWALDER, Jay A; CHERNEY, Emily Charlotte; SHAN, Weifang; HUANG, Audris

Compounds that modulate the oxidoreductase enzyme indoleamine 2,3- dioxygenase, and compositions containing the compounds, are described herein. The use of such compounds and compositions for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders, that are mediated by indoleamine 2,3-dioxygenase is also provided.

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Application of 54569-28-7, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.54569-28-7, Name is 4-Bromo-1,8-naphthyridine, molecular formula is C8H5BrN2. In a article£¬once mentioned of 54569-28-7

CECEP Wanrun Co., Ltd.; Sheng Lei; Zhang Chengxin; Shi Yu; Chi Pengli; Dai Shuhua; Zhou Peng

The invention relates to a kind of the organic light-emitting diode (OLED) material and its application, this material has […] (I) indicated by the structure, wherein the Ar containing substituent or not containing substituent of the aromatic ring or aromatic heterocycle, R1, R2, R4 – R8 is independently selected from hydrogen, cyano, C1 – C40 alkyl, alkoxy or aromatic, R3 is selected from hydrogen atom, containing substituent or not containing substituent of the aromatic ring or aromatic heterocycle, the material can be used as small molecule OLED device functional layer, application in organic electroluminescence in the field. (by machine translation)

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Gilead Sciences, Inc.; Chin, Gregory; Clarke, Michael O’ Neil Hanrahan; Han, Xiaochun; Hansen, Tim; Hu, Yunfeng Eric; Koltun, Dmitry; McFadden, Ryan; Mish, Michael R.; Parkhill, Eric Q.; Sperandio, David; Xu, Lianhong; Yang, Hai

The present disclosure provides a compound of Formula (I): or a pharmaceutically acceptable salt thereof as described herein. The present disclosure also provides pharmaceutical compositions comprising a compound of Formula I, processes for preparing compounds of Formula I, therapeutic methods for treating cancers.

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One of the oldest and most widely used commercial enzyme inhibitors is aspirin, HPLC of Formula: C8H5BrN2, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 54569-28-7

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PETRA PHARMA CORPORATION; KESICKI, Edward A.; RAVI, Kannan Karukurichi; LINDSTROeM, Johan; PERSSON, Lars Boukharta; LIVENDAHL, Madeleine; VIKLUND, Jenny; GINMAN, Tobias; FORSBLOM, Rickard; RAHM, Fredrik; HICKEY, Eugene R.; DAHLGREN, Markus K.; GERASYUTO, Aleksey I.

The invention relates to inhibitors of PI5P4K inhibitors useful in the treatment of cancers, neurodegenerative diseases, inflammatory disorders, and metabolic diseases, having the Formula (I): wherein A, X, Y, Z, Q, R1, R2, R3, R4, R5, and n are described herein.

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Chemistry is traditionally divided into organic and inorganic chemistry. Formula: C8H5BrN2, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent£¬Which mentioned a new discovery about 54569-28-7

MERCK PATENT GMBH; SHERER, Brian A.; BRUGGER, Nadia

The present invention relates to compounds of Formula (I) and pharmaceutically acceptable compositions thereof, useful as toll-like receptor 7/8 (TLR7/8) antagonists. In Formula (I), Ring A is aryl or heteroaryl; Ring B is aryl or heteroary; and X is C(R4)2, O, NR4, S, S(R4), or S(R4)2.

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Application of 54569-28-7, Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 54569-28-7, molcular formula is C8H5BrN2, introducing its new discovery.

Shanghai Tianma Organic Shine Display Co., Ltd.; Zhang Lei; Wang Xiangcheng; Gao Wei; Niu Jinghua

The invention relates to the field of luminescent material, in particular to a compound and its preparation method, an organic light-emitting display device. The compounds have the structure shown below: This compound is used for organic electroluminescent devices, can be used as the main material, doped material, a hole transporting layer material, the electron transport layer material, the cap layer material, can reduce the driving voltage, improve the luminous efficiency, brightness, thermal stability, color purity and service life of the device. (by machine translation)

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Reference£º
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