Category: 5175-14-4

As a common heterocyclic compound, it belongs to naphthyridine compound, name is 2-Oxo-1,2-dihydro-1,8-naphthyridine-3-carboxylic acid, and cas is 5175-14-4, its synthesis route is as follows.

Step 3: 3-Bromo-l,8-naphthyridin-2-olA solution of bromine (3.78 g, 23.7 mmol) in pyridine (4 mL) and DMF (8 mL) was added to the product of Step 2 (450 mg, 2.37 mmol) and heated at 1050C for 1 hour. The reaction was cooled; H2O was added, and the mixture filtered. The filtrate was extracted with EtOAc (2x). The organic layers washed with brine and saturated NH4Cl(aq.) and dried over Na2SO4. The solvent was concentrated in vacuo, and the resulting gum was triturated with DCM, and filtered to give a brown solid (156 mg) as desired product. M+H = 224.9.

5175-14-4, In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles.,5175-14-4 ,2-Oxo-1,2-dihydro-1,8-naphthyridine-3-carboxylic acid, other downstream synthetic routes, hurry up and to see

Reference£º
Patent; MERCK & CO., INC.; ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A.; WO2008/57209; (2008); A1;,
1,8-Naphthyridine – Wikipedia
1,8-Naphthyridine | C8H6N2 – PubChem

Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. COA of Formula: C9H6N2O3. Introducing a new discovery about 5175-14-4, Name is 2-Oxo-1,2-dihydro-1,8-naphthyridine-3-carboxylic acid

MERCK & CO., INC.; ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A.

The present invention relates to macrocyclic compounds of formula (I) that are useful as inhibitors of the hepatitis C virus (HCV) NS3 protease, their synthesis, and their use for treating or preventing HCV infections.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.COA of Formula: C9H6N2O3, you can also check out more blogs about5175-14-4

Reference£º
1,524-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N518 – PubChem

2-Oxo-1,2-dihydro-1,8-naphthyridine-3-carboxylic acid, cas is 5175-14-4, it is a common heterocyclic compound, the naphthyridine compound, its synthesis route is as follows.

5175-14-4, Step 3: 3-Bromo-l,8-naphthyridin-2-olA solution of bromine (3.78 g, 23.7 mmol) in pyridine (4 mL) and DMF (8 mL) was added to the product of Step 2 (450 mg, 2.37 mmol) and heated at 1050C for 1 hour. The reaction was cooled; H2O was added, and the mixture filtered. The filtrate was extracted with EtOAc (2x). The organic layers washed with brine and saturated NH4Cl(aq.) and dried over Na2SO4. The solvent was concentrated in vacuo, and the resulting gum was triturated with DCM, and filtered to give a brown solid (156 mg) as desired product. M+H = 224.9.

With the rapid development of chemical substances, we look forward to future research findings about 2-Oxo-1,2-dihydro-1,8-naphthyridine-3-carboxylic acid

Reference£º
Patent; MERCK & CO., INC.; ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A.; WO2008/57209; (2008); A1;,
1,8-Naphthyridine – Wikipedia
1,8-Naphthyridine | C8H6N2 – PubChem