Category: 35192-05-3

Reference of 35192-05-3, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.35192-05-3, Name is 2-Chloro-1,7-naphthyridine, molecular formula is C8H5ClN2. In a Patent£¬once mentioned of 35192-05-3

Zhejiang Huaxian Optoelectric Technology Co., Ltd.; Gao Chunji; Wang Huayue; Qian Ye; Huang Di

The present invention discloses a green phosphorescent compound and an organic electroluminescent device, using the compound as a dopant of a green phosphorescent compound represented by Formula, below an anode, hole injection layer, hole transport layer, emission layer, electron injection layer and a cathode, (I) which are sequentially deposited with each other. Formula I wherein, R1 , R2 , R3 , R4 , R5 , R6 , R7 , R8 , R9 And R10 Independently selected from hydrogen, deuterium, halogen, alkyl, cycloalkyl, heteroalkyl, aryl alkyl, alkoxy, aryl, alkyl, alkynyl, aryl-cycloalkenyl,isobutyronitrile, isobutyronitrile, sulphonyl, sulphinyl,X sulfonyl, phosphonylsulphonylsulphonylsulphonylphosphoryl and combinations, thereof. 1 X X-ray tube11 A compound selected from C or N;X selected from substituted or unsubstituted naphthyridine ;Y selected from substituted or unsubstituted phenyl, pyridine, pyrimidine, pyrazine, pyridazine ;n selected from 0, 1 or 2. (by machine translation)

We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 35192-05-3, and how the biochemistry of the body works.Reference of 35192-05-3

Reference£º
1,472-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N466 – PubChem

35192-05-3, Chemistry is traditionally divided into organic and inorganic chemistry. The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent£¬Which mentioned a new discovery about 35192-05-3

AMGEN INC.

Selected compounds are effective for prophylaxis and treatment of diseases, such as angiogenesis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

One of the oldest and most widely used commercial enzyme inhibitors is aspirin, 35192-05-3, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 35192-05-3

Reference£º
1,473-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N467 – PubChem

As a common heterocyclic compound, it belong naphthyridine compound,2-Chloro-1,7-naphthyridine,35192-05-3,Molecular formula: C8H5ClN2,mainly used in chemical industry, its synthesis route is as follows.,35192-05-3

2-Chlorb-[l,7]naphthyridine (100 mg, 0.61 mmol) , 2-amino-N- (4- tert-butyl-phenyl) -benzamide (164 mg, 0.61 mmol),Pd2(dba)3 (6 mg, 0.006 mmol), (2 ‘ -Dicyclohexylphosphanyl-biphenyl – 2 -yl) -dimethyl -amine (6 mg, 0.015 mmol), and 1Msolution of LiN(TMS)2 in THF (1.83 inL) , 1.83 mmol) wereadded to a reaction vessel. The vessel was sealed and thereaction was stirred at 70 aC for 24h. The mixture wascooled to RT, and solvent was removed under vacuum. Thecrude was purified by flash column chromatography (gradiant,0 to 100% EtoAC/Hexane) to give the product as tan solid. MS(ES~) : 397.0 (M+H) + . Calc’d for C25H24N40 – 396.20.

With the synthetic route has been constantly updated, we look forward to future research findings about 2-Chloro-1,7-naphthyridine,belong naphthyridine compound

Reference£º
Patent; AMGEN INC.; WO2006/12374; (2006); A1;,
1,8-Naphthyridine – Wikipedia
1,8-Naphthyridine | C8H6N2 – PubChem

It is a common heterocyclic compound, the naphthyridine compound, 2-Chloro-1,7-naphthyridine, cas is 35192-05-3 its synthesis route is as follows.,35192-05-3

Step B: Preparation of 4, [4-DIMETHYL-7- [2- ( [1,] 7] [NAPHTHYRIDIN-2-YLAMINO)-BENZOYLAMINO]-3, 4-DIHYDRO-LH-] isoquinoline-2-carboxylic acid tert-butyl ester A mixture of [7- (2-AMINO-BENZOYLAMINO)-4,] 4-dimethyl- 3, [4-DIHYDRO-LH-ISOQUINOLINE-2-CARBOXYLIC] acid tert-butyl ester (Step A, 303 mg, 0.77 mmol), 2-chloro- [1, 7] [NAPHTHYRIDINE (126] mg, 0. [77 MMOL), PD2 (DBA)] 3 (7.1 mg, 0.008 [MMOL),] 2-dicyclohexyl [PHOSPHINO-2′- (N-N-] dimethyamino) biphenyl (8 mg, 0.02 [MMOL),] and LiN (TMS) 2 (1 M solution in THF, 2.3 mL) was heated at [80 C] for 12 h. The mixture was concentrated in vacuo and the crude material was purified with flash chromatography [(SI02,] 5% [MEOH/CH2CL2)] to obtain the titled compound. MS [(ES+)] : 524.0 [(M+H) +. CALC’D] for [C31H33NSO3-523.] 63.

With the complex challenges of chemical substances, we look forward to future research findings about 2-Chloro-1,7-naphthyridine

Reference£º
Patent; AMGEN INC.; WO2004/5279; (2004); A2;,
1,8-Naphthyridine – Wikipedia
1,8-Naphthyridine | C8H6N2 – PubChem

2-Chloro-1,7-naphthyridine, cas is 35192-05-3, it is a common heterocyclic compound, the naphthyridine compound, its synthesis route is as follows.

Step B: Preparation of [N- (4-TERT-BUTYL-PHENYL)-2- ( [1, 7]] naphthyridin-2-ylamino)-benzamide A mixture of [2-AMINO-N- (4-TERT-BUTYL-PHENYL)-BENZAMIDE] (Step A, 163 mg, 0.61 mmol), [2-CHLORO- [1,] 7] naphthyridine [(100] mg, 0.61 [MMOL),] [PD2 (DBA)] 3 (6.0 mg, 0. [006] mmol), 2- dicyclohexyl [PHOSPHINO-2′- (N-N-DIMETHYAMINO)] biphenyl (6.0 mg, 0.015 mmol), and LiN (TMS) 2 (1 M solution in THF, 2.3 mL) was heated at [80 C] for 12 h in a sealed tube. The mixture was concentrated in vacuo and the crude material was purified with flash chromatography [(SI02,] [20%] EtOAc/hexane) and crystallization from EtOH to give the desired compound. MS [(ES+)] : [397.] 0 (M+H) [+.] Calc’d for [C25H24N4O-396.] 48.

35192-05-3, As the rapid development of chemical substances, we look forward to future research findings about 35192-05-3

Reference£º
Patent; AMGEN INC.; WO2004/5279; (2004); A2;,
1,8-Naphthyridine – Wikipedia
1,8-Naphthyridine | C8H6N2 – PubChem

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.35192-05-3,2-Chloro-1,7-naphthyridine,as a common compound, the synthetic route is as follows.

2-Chlorb-[l,7]naphthyridine (100 mg, 0.61 mmol) , 2-amino-N- (4- tert-butyl-phenyl) -benzamide (164 mg, 0.61 mmol),Pd2(dba)3 (6 mg, 0.006 mmol), (2 ‘ -Dicyclohexylphosphanyl-biphenyl – 2 -yl) -dimethyl -amine (6 mg, 0.015 mmol), and 1Msolution of LiN(TMS)2 in THF (1.83 inL) , 1.83 mmol) wereadded to a reaction vessel. The vessel was sealed and thereaction was stirred at 70 aC for 24h. The mixture wascooled to RT, and solvent was removed under vacuum. Thecrude was purified by flash column chromatography (gradiant,0 to 100% EtoAC/Hexane) to give the product as tan solid. MS(ES~) : 397.0 (M+H) + . Calc’d for C25H24N40 – 396.20., 35192-05-3

35192-05-3 2-Chloro-1,7-naphthyridine 20696625, anaphthyridine compound, is more and more widely used in various fields.

Reference£º
Patent; AMGEN INC.; WO2006/12374; (2006); A1;,
1,8-Naphthyridine – Wikipedia
1,8-Naphthyridine | C8H6N2 – PubChem