Category: 2960-93-2

Wu, Haibo published the artcileEnantiorecognition ability of peptoids with α-chiral, aromatic side chains, Related Products of naphthyridine, the publication is Analyst (Cambridge, United Kingdom) (2011), 136(21), 4409-4411, database is CAplus and MEDLINE.

The enantiorecognition ability of oligomeric N-substituted glycines or “peptoids” with α-chiral, aromatic side chains was investigated by HPLC and ¹H NMR studies. For example, (S)-N-(1-phenylethyl)glycine (Nspe) was used as the monomer for the peptoids. The peptoids were synthesized with chloroacetyl chloride and (S)-α-phenylethylamine as submonomers in a homogeneous phase reaction. A series of peptoids with three to seven Nspe units were synthesized, followed by reaction with triethoxy (3-isocyanatopropyl)silane to generate the corresponding chiral monomers, and then, covalently bonded to the surface of spherical silica gel to obtain chiral stationary phases (CSPs 1-5). The chiral separation abilities of the CSPs for racemic BINOL and its derivatives were found to significantly depend on the chain length of the chiral selectors. The min. structural units required for resolving BINOL was found to be three. The enantioselectivities of of CSP-3 and CSP-4 were further evaluated by HPLC using 52 chiral analytes of wide structural variety. It was observed that possession of hydrogen bonding donors is a precondition for successful resolution on peptoid CSP.

Analyst (Cambridge, United Kingdom) published new progress about 2960-93-2. 2960-93-2 belongs to naphthyridine, auxiliary class Naphthalene,Ether,Other MOF ligands,Organic ligands for MOF materials, name is 2,2′-Dimethoxy-1,1′-binaphthalene, and the molecular formula is C20H22ClN3O3, Related Products of naphthyridine.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Huang, Junmin published the artcileHighly efficient chromatographic resolution of α,α’-dihydroxybiaryls, Formula: C22H18O2, the publication is Organic Letters (2005), 7(26), 5821-5823, database is CAplus and MEDLINE.

Separation factors ≤115 were observed for the chromatog. resolution of many α,α’-dihydroxybiaryls with a single chiral stationary phase made from readily available amino acid derivatives The stationary phase works well for biphenyl-type compounds It works extremely well for larger bis-aromatic compounds, such as binaphthyl-type compounds

Organic Letters published new progress about 2960-93-2. 2960-93-2 belongs to naphthyridine, auxiliary class Naphthalene,Ether,Other MOF ligands,Organic ligands for MOF materials, name is 2,2′-Dimethoxy-1,1′-binaphthalene, and the molecular formula is C22H18O2, Formula: C22H18O2.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Mu, Bing published the artcileSynthesis of symmetrical biaryls by cyclopalladated ferrocenylimine catalyzed ullmann-type coupling reaction, Related Products of naphthyridine, the publication is Henan Shifan Daxue Xuebao, Ziran Kexueban (2013), 41(5), 81-85, database is CAplus.

Cyclopalladated ferrocenylimine was tested as catalyst in the Ullmann-type coupling reaction in the presence of ¹Pr₂NEt as base and DMF as solvent under Ar conditions. The preparation of aromatic iodide comprises: diazotization reaction of substituted aniline with aqueous sodium nitrite solution in the presence of concentrated sulfuric acid to obtain substituted iodobenzene, adding with potassium iodide, placing in refrigerator for 2-3 h, adjusting with NaOH to alk., extracting with dichloromethane, drying with anhydrous magnesium sulfate. It offered excellent yields in the coupling reaction of electronically and structurally diverse aryl iodides. Herein we have developed a simple, efficient way to synthesize sym. biaryls.

Henan Shifan Daxue Xuebao, Ziran Kexueban published new progress about 2960-93-2. 2960-93-2 belongs to naphthyridine, auxiliary class Naphthalene,Ether,Other MOF ligands,Organic ligands for MOF materials, name is 2,2′-Dimethoxy-1,1′-binaphthalene, and the molecular formula is C22H18O2, Related Products of naphthyridine.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Zhao, Qing published the artcileAn Efficient Method for Sterically Demanding Suzuki-Miyaura Coupling Reactions, Product Details of C22H18O2, the publication is Chemistry – A European Journal (2013), 19(7), 2261-2265, database is CAplus and MEDLINE.

The synthesis of tetra-ortho-substituted biaryls bearing secondary alkyl ortho substituents, such as iso-Pr groups, through Suzuki-Miyaura couplings was catalyzed by Pd(OAc)₂ and a biaryl monophosphorus ligand, e.g. I. E.g., in presence of Pd(OAc)₂, I, and NaOtBu, Suzuki-Miyaura coupling of 2-bromo-1,3-dimethoxybenzene and 2,4,6-triisopropylphenylboronic acid gave 97% tetra-ortho-substituted biaryl (II).

Chemistry – A European Journal published new progress about 2960-93-2. 2960-93-2 belongs to naphthyridine, auxiliary class Naphthalene,Ether,Other MOF ligands,Organic ligands for MOF materials, name is 2,2′-Dimethoxy-1,1′-binaphthalene, and the molecular formula is C18H34N4O5S, Product Details of C22H18O2.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Pan, Wenjing published the artcileA mild and practical method for deprotection of aryl methyl/benzyl/allyl ethers with HPPh₂ and ^tBuOK, Category: naphthyridine, the publication is Organic & Biomolecular Chemistry (2021), 19(35), 7633-7640, database is CAplus and MEDLINE.

A general method for the demethylation, debenzylation, and deallylation of aryl ethers ROMe (R = C₆H₅, 3-FC₆H₄, 2-naphthyl, etc.), R¹OCH²Ph (R¹ = C₆H₅, 5,6,7,8-tetrahydronaphthalen-2-yl, 2-naphthyl, etc.) and R²OCH²CH=CH² (R² = C₆H₅, 2,3-dimethylphenyl, 1-naphthyl, etc.) using HPPh₂ and ^tBuOK is reported. The reaction features mild and metal-free reaction conditions, broad substrate scope, good functional group compatibility, and high chem. selectivity towards aryl ethers over aliphatic structures. Notably, this approach is competent to selectively deprotect the allyl or benzyl group, making it a general and practical method in organic synthesis.

Organic & Biomolecular Chemistry published new progress about 2960-93-2. 2960-93-2 belongs to naphthyridine, auxiliary class Naphthalene,Ether,Other MOF ligands,Organic ligands for MOF materials, name is 2,2′-Dimethoxy-1,1′-binaphthalene, and the molecular formula is C22H18O2, Category: naphthyridine.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Maeyama, Katsuya published the artcileNickel complex-mediated synthesis of optically active wholly aromatic polyketones bearing 2,2′-dimethoxy-1,1′-binaphthyl-6,6′-ene units, Safety of 2,2′-Dimethoxy-1,1′-binaphthalene, the publication is Polymer Journal (Tokyo, Japan) (2005), 37(10), 736-741, database is CAplus.

Two 6,6′-Bis(chlorobenzoyl)-2,2′-dimethoxy-1,1′-binaphthyls (3,3′-Cl and 4,4′-Cl) are prepared via P₂O₅-MsOH mediated regioselective diaroylation of 2,2′-dimethoxy-1,1′-binaphthyl. NiBr₂/Zn-mediated aromatic coupling polymerization of 6,6′-bis(chlorobenzoyl)-2,2′-dimethoxy-1,1′-binaphthyls yields the corresponding wholly aromatic polyketones. When optically active bis(chlorobenzoylated) binaphthyls are employed, optically active wholly aromatic polyketones with large sp. rotations, excellent thermal resistance, and excellent solubility to organic solvents are obtained.

Polymer Journal (Tokyo, Japan) published new progress about 2960-93-2. 2960-93-2 belongs to naphthyridine, auxiliary class Naphthalene,Ether,Other MOF ligands,Organic ligands for MOF materials, name is 2,2′-Dimethoxy-1,1′-binaphthalene, and the molecular formula is C22H18O2, Safety of 2,2′-Dimethoxy-1,1′-binaphthalene.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Lee, Yong-Kyung published the artcileFree-Radical Polymerization of (R)-(-)-1-(1-Naphthyl)ethyl(2-methacryloyloxyethyl)urea and Chiral Recognition Ability, Safety of 2,2′-Dimethoxy-1,1′-binaphthalene, the publication is Macromolecules (2003), 36(13), 4735-4742, database is CAplus.

(R)-(-)-1-(1-Naphthyl)ethyl(2-methacryloyloxyethyl)urea (NEMOU) was synthesized from 2-methacryloyloxyethyl isocyanate (MOI) and (R)-(+)-1-(1-naphthyl)ethylamine. Radical homopolymerizations of NEMOU were performed in several solvents to obtain the corresponding chiral polymers that have hydrogen bonds based on urea moieties. Specific optical rotations of poly(NEMOU) changed by the measurement temperature, which may be attributed in part to change of conformation. From the results of radical copolymerizations of NEMOU with styrene (ST, M₂) or Me methacrylate (MMA, M₂), monomer reactivity ratios (r₁, r₂) and Alfrey-Price Q-e were determined: r₁ = 0.48, r₂ = 0.20, Q₁ = 1.41, e₁ = 0.74 for the NEMOU-ST system; r₁ = 0.55, r₂ = 0.16, Q₁ = 9.02, e₁ = 1.96 for the NEMOU-MMA system. The chiroptical property of the copolymers was strongly influenced by comonomer units. To examine the chiral recognition ability of poly(NEMOU), chiral stationary phases (CSPs) for high-performance liquid chromatog. (HPLC) were prepared from silica gel and poly(NEMOU). The CSPs resolved some racemates such as 1,2,3,4-tetrahydro-1-naphthol and N-benzyl-1-(1-methyl-2-methoxycarbonyl)ethylamine in n-hexane/2-propanol as mobile phase by HPLC. The chiral recognition ability of poly(NEMOU) may be ascribed not only to the interaction between the low mol. weight chiral selector and the racemates but also to the secondary and/or higher-ordered structure of the polymer.

Macromolecules published new progress about 2960-93-2. 2960-93-2 belongs to naphthyridine, auxiliary class Naphthalene,Ether,Other MOF ligands,Organic ligands for MOF materials, name is 2,2′-Dimethoxy-1,1′-binaphthalene, and the molecular formula is C22H18O2, Safety of 2,2′-Dimethoxy-1,1′-binaphthalene.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Sancho, Raquel published the artcileMonolithic silica columns functionalized with substituted polyproline-derived chiral selectors as chiral stationary phases for high-performance liquid chromatography, Quality Control of 2960-93-2, the publication is Journal of Separation Science (2014), 37(20), 2805-2813, database is CAplus and MEDLINE.

In this study, two polyproline-derived chiral selectors are bonded to monolithic silica gel columns. In spite of high chiral selector coverage, the derivatization was found to have only a slight effect on the hydrodynamics of the mobile phase through the column. The enantioseparation ability of the resulting chiral monolithic columns was evaluated with a series of structurally diverse racemic test compounds When compared to analogous bead-based chiral stationary phases, higher enantioseparation and broader application domain were observed for monolithic columns. Moreover, the increase in flow rate produces a minor reduction of resolution, which permits to shorten anal. time. Addnl., increased loadability defines chiral polyproline derived monoliths as adequate for preparative chromatog.

Journal of Separation Science published new progress about 2960-93-2. 2960-93-2 belongs to naphthyridine, auxiliary class Naphthalene,Ether,Other MOF ligands,Organic ligands for MOF materials, name is 2,2′-Dimethoxy-1,1′-binaphthalene, and the molecular formula is C22H18O2, Quality Control of 2960-93-2.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Hirose, Daisuke published the artcileEnantioseparation on helical poly(diphenylacetylene)s bearing optically-active pendants: Effects of differences in higher-order structures of kinetically-trapped and thermodynamically-stable states on chiral recognition ability, Product Details of C22H18O2, the publication is Journal of Chromatography A (2022), 463164, database is CAplus and MEDLINE.

An optically-active poly(diphenylacetylene) (PDPA) bearing carboxy pendant groups with left-handed helicity memory (M-h-poly-1), synthesized using the noncovalent helicity-induction-and-memory strategy, was converted into a PDPA bearing optically-active pendant groups through an amide bonding (M-h_KT-poly-2S), while maintaining the left-handed helicity memory, by reaction with (S)-1-phenylethylamine ((S)-2) using a condensing reagent at room temperature Its chiral recognition ability was investigated as a chiral stationary phase (CSP) for high-performance liquid chromatog. (HPLC). M-h_KT-poly-2S exhibited significantly different chiral recognition ability towards racemates compared to the previously reported corresponding helical PDPA bearing the same optically-active pendant groups (M-h_TS-poly-2S) (prepared by the reaction of an optically-inactive PDPA bearing carboxy pendants with (S)-2, followed by thermal annealing, to induce a left-handed helical structure in the polymer main chain). Although the main chains of both M-h_KT-poly-2S and M-h_TS-poly-2S formed almost completely left-handed helical structures, their higher-order structures varied slightly, as confirmed by various spectroscopic methods (UV-Vis, CD (CD), IR, and vibrational CD). M-h_KT-TS-poly-2S, the PDPA formed on the thermal annealing of M-h_KT-poly-2S, exhibited the same higher-order structure and chiral discrimination ability as M-h_TS-poly-2S. Therefore, slight differences in the higher-order structures of the kinetically-trapped metastable state (M-h_KT-poly-2S) and the thermodynamically-stable state (M-h_TS-poly-2S), due to differences in synthetic procedures, significantly impact their chiral recognition abilities as CSPs, even with identical primary structures and helix-sense of the polymer main chain.

Journal of Chromatography A published new progress about 2960-93-2. 2960-93-2 belongs to naphthyridine, auxiliary class Naphthalene,Ether,Other MOF ligands,Organic ligands for MOF materials, name is 2,2′-Dimethoxy-1,1′-binaphthalene, and the molecular formula is C22H18O2, Product Details of C22H18O2.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Maeyama, Katsuya published the artcileP₂O₅-MsOH-mediated regioselective diaroylation of 2,2′-dimethoxy-1,1′-binaphthyl, Formula: C22H18O2, the publication is Synthetic Communications (2004), 34(17), 3243-3250, database is CAplus.

Phosphorus pentoxide-methanesulfonic acid (P₂O₅-MsOH) mediated electrophilic aromatic substitution diaroylation of 2,2′-dimethoxy-1,1′-binaphthyl with several aromatic carboxylic acids proceeds to afford 6,6′-diaroylated adducts as single regioisomers.

Synthetic Communications published new progress about 2960-93-2. 2960-93-2 belongs to naphthyridine, auxiliary class Naphthalene,Ether,Other MOF ligands,Organic ligands for MOF materials, name is 2,2′-Dimethoxy-1,1′-binaphthalene, and the molecular formula is C22H18O2, Formula: C22H18O2.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem