Category: 23616-31-1

Name is 1,6-Naphthyridin-5(6H)-one, as a common heterocyclic compound, it belongs to naphthyridine compound, and cas is 23616-31-1, its synthesis route is as follows.

[0622] A suspension of XI-3 (2.36 g, 15.7 mmol, 1 eq), N-bromosuccinimide (3.1 g, 17.3 mmol, 1 eq), and 50 mL of 1,2-dichloroethane was stirred at rt for 3.5 hrs. The mixture was filtered; the solids were washed successively with small amounts of chloroform, water, and diethyl ether, and then dried to leave XI-4 (0.8 g, 23percent yield). MS (ESI) m/z (M+H)+ 226.8.

23616-31-1, In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles.,23616-31-1 ,1,6-Naphthyridin-5(6H)-one, other downstream synthetic routes, hurry up and to see

Reference£º
Patent; Buckman, Brad Owen; Nicholas, John Beamond; Ramphal, Johnnie Y.; Emayan, Kumaraswamy; Seiwert, Scott D.; US2014/94456; (2014); A1;,
1,8-Naphthyridine – Wikipedia
1,8-Naphthyridine | C8H6N2 – PubChem

As a common heterocyclic compound, it belongs to quinuclidine compound,Quinuclidine-4-carboxylic acid hydrochloride,40117-63-3,Molecular formula: C8H14ClNO226,mainly used in chemical industry, its synthesis route is as follows.,23616-31-1

EXAMPLE 3 8Bromo-1,6-naphthyridine-5(6H) -one (5) A suspension of 1.462 g (10 mmol) of 1,6-naphthyridine-5(6H)-one (3), 1.96 g (11 mmol) of N-bromosuccinimide, and 30 mL of dry dichlorothane is stirred at 25¡ã C. for 3.5 hours. The mixture is filtered, the solids are washed successively with small amounts of chloroform, water, and ether, then dried to leave 2.0 g of white solid, mp 245¡ã-250¡ã C. This is combined with 348 mg from an earlier run. The solids are triturated in 15 mL of hot water, collected by filtration, and dried to leave 2.28 g of pure product, mp 247¡ã-251¡ã C. A suspension of 360 mg of the product in methanol is treated with an excess of 2-propanoic hydrogen chloride, heated for 3 to 5 minutes, and stored at 25¡ã C. for 1.5 hours. The solids are collected by filtration, washed with 2-propanol, and dried to give 410 mg of yellow powder as the hydrochloride salt, mp >245¡ã C. (decomposition).

With the complex challenges of chemical substances, we look forward to future research findings about 1,6-Naphthyridin-5(6H)-one,belong naphthyridine compound

Reference£º
Patent; Warner-Lambert Company; US5391554; (1995); A;,
1,8-Naphthyridine – Wikipedia
1,8-Naphthyridine | C8H6N2 – PubChem

23616-31-1, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 1,6-Naphthyridin-5(6H)-one, cas is 23616-31-1,the naphthyridine compound, it is a common compound, a new synthetic route is introduced below.

A suspension of XI-3 (2.36 g, 15.7 mmol, 1 eq), N-bromosuccinimide (3.1 g, 17.3 mmol, 1 eq), and 50 mL of 1,2-dichloroethane was stuffed at rt for 3.5 hrs. The mixture was filtered; the solids were washed successively with small amounts of chloroform, water, and diethyl ether, and then dried to leave XI-4 (0.8 g, 23percent yield). MS (ES) m/z (M+H) 226.8.

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 1,6-Naphthyridin-5(6H)-one, 23616-31-1

Reference£º
Patent; INTERMUNE, INC.; RAMPHAL, Johnnie, Y.; BUCKMAN, Brad, Owen; EMAYAN, Kumaraswamy; NICHOLAS, John, Beamond; SEIWERT, Scott, D.; WO2015/153683; (2015); A1;,
1,8-Naphthyridine – Wikipedia
1,8-Naphthyridine | C8H6N2 – PubChem

As a common heterocyclic compound, it belongs to naphthyridine compound, name is 1,6-Naphthyridin-5(6H)-one, and cas is 23616-31-1, its synthesis route is as follows.,23616-31-1

[0622] A suspension of XI-3 (2.36 g, 15.7 mmol, 1 eq), N-bromosuccinimide (3.1 g, 17.3 mmol, 1 eq), and 50 mL of 1,2-dichloroethane was stirred at rt for 3.5 hrs. The mixture was filtered; the solids were washed successively with small amounts of chloroform, water, and diethyl ether, and then dried to leave XI-4 (0.8 g, 23percent yield). MS (ESI) m/z (M+H)+ 226.8.

With the complex challenges of chemical substances, we look forward to future research findings about 23616-31-1,belong naphthyridine compound

Reference£º
Patent; Buckman, Brad Owen; Nicholas, John Beamond; Ramphal, Johnnie Y.; Emayan, Kumaraswamy; Seiwert, Scott D.; US2014/94456; (2014); A1;,
1,8-Naphthyridine – Wikipedia
1,8-Naphthyridine | C8H6N2 – PubChem

1,6-Naphthyridin-5(6H)-one, cas is 23616-31-1, it is a common heterocyclic compound, the naphthyridine compound, its synthesis route is as follows.

A suspension of XI-3 (2.36 g, 15.7 mmol, 1 eq), N-bromosuccinimide (3.1 g, 17.3 mmol, 1 eq), and 50 mL of 1,2-dichloroethane was stuffed at rt for 3.5 hrs. The mixture was filtered; the solids were washed successively with small amounts of chloroform, water, and diethyl ether, and then dried to leave XI-4 (0.8 g, 23percent yield). MS (ES) m/z (M+H) 226.8.

23616-31-1, With the rapid development of chemical substances, we look forward to future research findings about 1,6-Naphthyridin-5(6H)-one

Reference£º
Patent; INTERMUNE, INC.; RAMPHAL, Johnnie, Y.; BUCKMAN, Brad, Owen; EMAYAN, Kumaraswamy; NICHOLAS, John, Beamond; SEIWERT, Scott, D.; WO2015/153683; (2015); A1;,
1,8-Naphthyridine – Wikipedia
1,8-Naphthyridine | C8H6N2 – PubChem

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.23616-31-1,1,6-Naphthyridin-5(6H)-one,as a common compound, the synthetic route is as follows.

A suspension of XI-3 (2.36 g, 15.7 mmol, 1 eq), N-bromosuccinimide (3.1 g, 17.3 mmol, 1 eq), and 50 mL of 1,2-dichloroethane was stuffed at rt for 3.5 hrs. The mixture was filtered; the solids were washed successively with small amounts of chloroform, water, and diethyl ether, and then dried to leave XI-4 (0.8 g, 23percent yield). MS (ES) m/z (M+H) 226.8.

23616-31-1, As the paragraph descriping shows that 23616-31-1 is playing an increasingly important role.

Reference£º
Patent; INTERMUNE, INC.; RAMPHAL, Johnnie, Y.; BUCKMAN, Brad, Owen; EMAYAN, Kumaraswamy; NICHOLAS, John, Beamond; SEIWERT, Scott, D.; WO2015/153683; (2015); A1;,
1,8-Naphthyridine – Wikipedia
1,8-Naphthyridine | C8H6N2 – PubChem