Category: 14903-78-7

Fun, Hoong Kun published the artcile2,7-Dimethyl-1,8-naphthyridine, Computed Properties of 14903-78-7, the publication is Acta Crystallographica, Section E: Structure Reports Online (2009), 65(8), o1747, database is CAplus and MEDLINE.

The asym. unit of 2,7-di-Me-1,8-naphthyridine, C₁₀H₁₀N₂, contains 1/2-mol. with the 2 shared C atoms lying on a 2-fold rotation axis. The 1,8-naphthyridine is almost planar with a dihedral angle of 0.42(3)° between the fused pyridine rings. In the crystal, mols. are linked into infinite chains along the c axis by intermol. C-H···N H bonds, generating R₂²(8) ring motifs. The crystal structure is further stabilized by C-H···π interactions. Crystallog. data are given.

Acta Crystallographica, Section E: Structure Reports Online published new progress about 14903-78-7. 14903-78-7 belongs to naphthyridine, auxiliary class 6.6_Aromatics,Naphthyridines, name is 2,7-Dimethyl-1,8-naphthyridine, and the molecular formula is C10H10N2, Computed Properties of 14903-78-7.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Jones, Richard A. Y. published the artcileKinetics of quaternization of some naphthyridines and methylnaphthyridines, Related Products of naphthyridine, the publication is Chemical Communications (London) (1969), 56-7, database is CAplus.

The 2nd order rate constants for the reaction of MeI with some naphthyridines and methylnaphthridines in MeCN were determined by a conductimetric method. The following results were obtained at 24.8° (compound, and rate constant × 10-4 l./mole/sec. given): quinoline, 0.517; isoquinoline, 4.23; 1,5-naphthyridine, 0.232; 1,6-naphthyridine, 1.66; 1,8-naphthyridine, 4.25; 2-methyl-1,8-naphthyridine, 3.61; 3-methyl-1,8-naphthyridine, 5.74; 4-methyl-1,8-naphthyridine, 7.26; and 2,7-dimethyl-1,8-naphthyridine, 1.85. The rate constants are used to deduce the quaternization kinetics of the reactions.

Chemical Communications (London) published new progress about 14903-78-7. 14903-78-7 belongs to naphthyridine, auxiliary class 6.6_Aromatics,Naphthyridines, name is 2,7-Dimethyl-1,8-naphthyridine, and the molecular formula is C10H10N2, Related Products of naphthyridine.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Zimmerman, Steven C. published the artcileAnalysis of Amidinium Guest Complexation by Comparison of Two Classes of Dendrimer Hosts Containing a Hydrogen Bonding Unit at the Core, Synthetic Route of 14903-78-7, the publication is Journal of the American Chemical Society (1998), 120(9), 2172-2173, database is CAplus.

Host-guest complexation studies were performed using two isostructural series of hosts to determine the accessibility and nanoenvironment of dendrimer cores. Association constants (K_assoc) were measured by ¹H NMR for the hydrogen bonded complexes formed between hosts and guests 3,5-di-tert-Bu benzamidinium tetrakis[3,5-bis(trifluoromethyl)phenyl]borate and 3,5-bis(3′,5′-di-tert-butylphenylacetylene) tetrakis[3,5-bis(trifluoromethyl)phenyl]borate in 10% acetonitrile-d₃/chloroform-d. The results indicated site-specific binding between the dendrimer core and small guest mols. The on-off rates were fast on the NMR time scale even for complexes formed from high generation number hosts. Strikingly, the two series of dendritic hosts exhibited very similar complexation strengths even though the rigidity and polarity of the dendrimer interiors were quite different.

Journal of the American Chemical Society published new progress about 14903-78-7. 14903-78-7 belongs to naphthyridine, auxiliary class 6.6_Aromatics,Naphthyridines, name is 2,7-Dimethyl-1,8-naphthyridine, and the molecular formula is C17H14N2O2, Synthetic Route of 14903-78-7.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Vu, Choua published the artcileElaboration of 1,8-naphthyridine-2,7-dicarboxaldehyde into novel 2,7-dimethylimine derivatives, Name: 2,7-Dimethyl-1,8-naphthyridine, the publication is Journal of Heterocyclic Chemistry (2002), 39(4), 829-832, database is CAplus.

The condensation of 1,8-naphthyridine-2,7-dicarboxaldehyde, available by SeO₂ oxidation of 2,7-dimethyl-1,8-naphthyridine, with various primary amines RNH₂ (R = Me₃C, PhCH₂, EtSCH₂CH₂, cyclohexyl, 1-adamantyl) in MeOH afforded diimines I in reasonable to excellent yields (56-84%) after recrystallization Naphthyridines I typically displayed the NMR spectra consistent with a mirror plane perpendicular to the naphthyridine plane and syn,syn relationships of the naphthyridine moiety with each imine nitrogen lone pair.

Journal of Heterocyclic Chemistry published new progress about 14903-78-7. 14903-78-7 belongs to naphthyridine, auxiliary class 6.6_Aromatics,Naphthyridines, name is 2,7-Dimethyl-1,8-naphthyridine, and the molecular formula is C11H10O, Name: 2,7-Dimethyl-1,8-naphthyridine.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Behlen, Michael J. published the artcileC₂-Symmetric dinickel catalysts for enantioselective [4 + 1]-cycloadditions, Safety of 2,7-Dimethyl-1,8-naphthyridine, the publication is Journal of the American Chemical Society (2020), 142(41), 17294-17300, database is CAplus and MEDLINE.

Dinickel naphthyridine-bis(oxazoline) catalysts promote enantioselective intermol. [4 + 1]-cycloadditions of vinylidene equivalent and 1,3-dienes. The products of this reaction are methylenecyclopentenes, and the exocyclic alkene is generally obtained with high Z selectivity. E- and Z-dienes react in a stereoconvergent fashion, providing cycloadducts with the same sense of absolute stereochem. and nearly identical ee values. This feature allows dienes that are com. available as E/Z mixtures to be used as substrates for the cycloaddition A DFT model for the origin of asym. induction is provided.

Journal of the American Chemical Society published new progress about 14903-78-7. 14903-78-7 belongs to naphthyridine, auxiliary class 6.6_Aromatics,Naphthyridines, name is 2,7-Dimethyl-1,8-naphthyridine, and the molecular formula is C10H10N2, Safety of 2,7-Dimethyl-1,8-naphthyridine.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Weissenfels, Manfred published the artcilePhotocatalytic systems. VIII. Preparation of 1,8-naphthyridine aldehydes, Formula: C10H10N2, the publication is Zeitschrift fuer Chemie (1978), 18(1), 20-1, database is CAplus.

Oxidation of methylnaphthyridines I (R = Me, R¹ = H, Me) with SeO₂ gave the corresponding aldehydes I (R = CHO, R¹ = H, CHO), characterized as the oximes, semicarbazones, etc. Benzoin reaction of I (R = CHO, R¹ = H) gave II, which was oxidized by air to III.

Zeitschrift fuer Chemie published new progress about 14903-78-7. 14903-78-7 belongs to naphthyridine, auxiliary class 6.6_Aromatics,Naphthyridines, name is 2,7-Dimethyl-1,8-naphthyridine, and the molecular formula is C5H10N2OS, Formula: C10H10N2.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Tiripicchio, Antonio published the artcileComplexes of rhodium(I) with 1,8-naphthyridine and related ligands. Crystal structure of bis(μ-1,8-naphthyridine-N,N’)bis[(η-2,5-norbornadiene)rhodium(I)](Rh-Rh) diperchlorate monohydrate, Computed Properties of 14903-78-7, the publication is Journal of the Chemical Society, Dalton Transactions: Inorganic Chemistry (1972-1999) (1984), 125-31, database is CAplus.

A series of Rh complexes with 1,8-naphthyridine (L) or its 2-Me (L¹) and 2,7-di-Me analogs was prepared by substitution of the corresponding (diene)Rh complexes. E.g., treating [L²Rh(OCMe₂)_n](ClO₄) (L² = 2,5-norbornadiene) with L in Me₂CO gave the title compound, [(μ-L)₂Rh₂L²₂](ClO₄), isolated as its monohydrate (I). The structure of I was determined by x-ray crystallog. I is binuclear, with 2 L ligands bridging the 2 Rh atoms. Aged samples of the related complexes [L₂Rh₂(CO)₄](ClO₄) and [L¹₂Rh₂(CO)₄](ClO₄) exploded violently during microanal.

Journal of the Chemical Society, Dalton Transactions: Inorganic Chemistry (1972-1999) published new progress about 14903-78-7. 14903-78-7 belongs to naphthyridine, auxiliary class 6.6_Aromatics,Naphthyridines, name is 2,7-Dimethyl-1,8-naphthyridine, and the molecular formula is C6H9N3, Computed Properties of 14903-78-7.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Newkome, George R. published the artcileFunctionalization of 2-methyl- and 2,7-dimethyl-1,8-naphthyridine, Formula: C10H10N2, the publication is Journal of Organic Chemistry (1990), 55(9), 2838-42, database is CAplus.

2,7-Dimethyl-1,8-naphthyridine (I) was prepared from 2-methyl-1,8-naphthyridine (II) by reaction with 3 equiv of MeLi. Oxidation of I with 8 equiv of N-chlorosuccinimide gave 98% naphthyridine III (R = R¹ = CCl₃) (IV), while oxidation with 4 equiv gave 97% III (R = R¹ = CHCl₂). Hydrolysis of IV with H₃PO₄ followed by esterification gave the diester III (R = R¹ = CO₂Me) (V) in 80% overall yield. Reduction of V with NaBH(OMe)₃ afforded 55% III (R = R¹ = CH₂OH). Similar functionalization of II afforded III (R = H, R¹ = CCl₃) (VI) in 85-94% yield, along with 6-chloro-2-(trichloromethyl)-1,8-naphthyridine. Methanolysis of VI gave 78% III (R = H, R¹ = CO₂Me), which on reduction with NaBH(OMe)₃ afforded 59% III (R = H, R¹ = CH₂OH). Treatment of VI with KOH caused a displacement of the trichloromethyl moiety, generating 1,8-naphthyridin-2-one VII (R¹ = H) as the sole product. Similarly, IV gave VII (R¹ = CCl₃) under mild conditions or a mixture of VII (R¹ = CO₂Et, CCl₃) when refluxed in EtOH.

Journal of Organic Chemistry published new progress about 14903-78-7. 14903-78-7 belongs to naphthyridine, auxiliary class 6.6_Aromatics,Naphthyridines, name is 2,7-Dimethyl-1,8-naphthyridine, and the molecular formula is C10H10N2, Formula: C10H10N2.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Mastalarz, H. published the artcileThe synthesis of some 2,7-disubstituted 1,8-naphthyridines, Synthetic Route of 14903-78-7, the publication is Polish Journal of Chemistry (1994), 68(3), 459-65, database is CAplus.

The reaction of 2,7-dichloro-1,8-naphthyridine (I) with the Na salts of some active methylene compounds is described. The resulting 7-chloro-2-substituted and 2,7-disubstituted 1,8-naphthyridine derivatives exist in 2(1H)-naphthryidine form. The reactions of 2,7-dichloro-1,8-naphthyridine with diethanolamine, hydrolysis and acid-catalyzed decomposition for some of the obtained compounds were also reported.

Polish Journal of Chemistry published new progress about 14903-78-7. 14903-78-7 belongs to naphthyridine, auxiliary class 6.6_Aromatics,Naphthyridines, name is 2,7-Dimethyl-1,8-naphthyridine, and the molecular formula is C10H10N2, Synthetic Route of 14903-78-7.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Hendricker, David G. published the artcileNaphthyridine complexes of Group VIb metal carbonyls, SDS of cas: 14903-78-7, the publication is Inorganic Chemistry (1969), 8(3), 685-7, database is CAplus.

M(CO)6 (M = Cr, Mo, W) and 2,7-dimethyl-1,8-naphthyridine (L) were refluxed in octane to afford M(CO)4L which were characterized by ir spectra. Also prepared were M(CO)4L’ (L’ = 2,9-dimethyl-1,10-phenanthroline). The ir spectra of M(CO)4L and M(CO)4L’ in the CO stretching region are very similar in number, position, and intensity of absorptions of the analogous complexes of 2,2′-bipyridine and 1,10-phenanthroline. The π-bonding ability of L and L’ is discussed on the basis of the force constants Preliminary investigations of substitution reactions of M(CO)4L with various monodentate ligands indicate that the reaction rate is similar to that reported for complexes containing 5-member chelate rings and thus suggests similar labilizing properties.

Inorganic Chemistry published new progress about 14903-78-7. 14903-78-7 belongs to naphthyridine, auxiliary class 6.6_Aromatics,Naphthyridines, name is 2,7-Dimethyl-1,8-naphthyridine, and the molecular formula is C10H10N2, SDS of cas: 14903-78-7.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem