Synthetic Route of 100361-18-0, Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 100361-18-0, molcular formula is C12H8ClFN2O3, introducing its new discovery.
DONG WHA PHARM. CO., LTD.; CHOI, Dong-Rack; LIM, Jae-Kyung; CHOI, Jung-Uk; SHIN, Dong-Hyuk; KIM, Seung-Hwan; WON, Dae-Yeon; KIM, Jung-Hwan
The present invention provides an improved method of manufacturing Zabofloxacin D-aspartate. The present invention provides a novel method of manufacturing 8-methoxyimino-2,6-diaza-spiro[3,4]octane-2-carboxylic acid t-butyl ester succinate (TBDCS) or 2-(2,2,2-trifluoro-acetyl)-2,6-diaza-spiro[3,4]octan-8-one O-methyloxime methanesulfonate (TDMOS), which are separately the starting materials for manufacturing Zabofloxacin D-aspartate. The manufacturing method according to the present invention is suitable for mass production of Zabofloxacin D-aspartate for it enables manufacturing in high yield and high quality (HPLC purity ? 99.5%) as well as reducing the unit cost of production by using only 1.0~1.1 equivalents of TBDCS or TDMOS in a substitution reaction.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 100361-18-0 is helpful to your research. Synthetic Route of 100361-18-0
Reference£º
1,662-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N656 – PubChem