Zheng, Yu’s team published research in Organic Letters in | CAS: 53731-26-3

Organic Letters published new progress about 53731-26-3. 53731-26-3 belongs to naphthyridine, auxiliary class Difluoromethyl,Fluoride,Naphthalene, name is 1-(Difluoromethyl)naphthalene, and the molecular formula is C23H20BN, Application In Synthesis of 53731-26-3.

Zheng, Yu published the artcilePhosphonium Ylide-Mediated Programmable Fluorination to Access Mono- and Difluoromethylarenes, Application In Synthesis of 53731-26-3, the publication is Organic Letters, database is CAplus and MEDLINE.

Compounds bearing fluorinated moieties are pervasive in a wide range of pharmaceuticals and agrochems. The installation of fluorinated units is a persistently vital task in synthetic chem., where facile and manipulable assays are highly demanding. Herein, we establish a general and programmable fluorination strategy for the modular assembly of mono- and difluoromethylarenes through the controllable deprotonation and fluorination of phosphonium ylides. Moreover, the rational combination of the reaction sequence allows the rapid construction of diversified fluorine-containing arenes.

Organic Letters published new progress about 53731-26-3. 53731-26-3 belongs to naphthyridine, auxiliary class Difluoromethyl,Fluoride,Naphthalene, name is 1-(Difluoromethyl)naphthalene, and the molecular formula is C23H20BN, Application In Synthesis of 53731-26-3.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem