Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 1569-17-1, is researched, SMILESS is CC1=C2C=CC=NC2=NC=C1, Molecular C9H8N2Journal, Chemische Berichte called Vicarious nucleophilic substitution of hydrogen, bisannulation and competitive reactions of α-haloalkyl carbanions with bicyclic azaaromatic compounds, Author is Makosza, Mieczyslaw; Golinski, Jerzy; Ostrowski, Stanislaw; Rykowski, Andrzej; Sahasrabudhe, Arvind B., the main research direction is quinoxaline vicarious nucleophilic substitution halomethyl carbanion; naphthyridine vicarious nucleophilic substitution halomethyl carbanion; azaquinoxaline vicarious nucleophilic substitution halomethyl carbanion; pyridopyrazine vicarious nucleophilic substitution halomethyl carbanion; heteroaromatic vicarious nucleophilic substitution halomethyl carbanion; bicyclic heteroaromatic annulation halomethyl carbanion.HPLC of Formula: 1569-17-1.
Carbanions of RR1CHSO2R2 (I; R = Cl, R1 = H, Me, R2 = NMe2, Ph, CMe3, morpholino, tolyl; R = Br, R1 = H, R2 = tolyl) react with bicyclic heteroaromatic compounds (quinoxalines, naphthyridines, and 5-azaquinoxalines) according to 2 general pathways: vicarious nucleophilic substitution (VNS) of hydrogen and/or bisannulation. In some cases other competitive reactions are observed Factors governing the direction of these reactions are discussed in terms of the charge distribution in the anionic σ adducts and the reaction conditions. For example reaction of quinoxaline and quinoxaline N-oxide with I (R = Cl, R1 = H, R2 = Ph) gave bisazirinoquinoxaline II and VNS product III resp.
Here is just a brief introduction to this compound(1569-17-1)HPLC of Formula: 1569-17-1, more information about the compound(4-Methyl-1,8-naphthyridine) is in the article, you can click the link below.
Reference:
1,8-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N2 – PubChem