When developing chemical systems it’s of course important to gain a deep understanding of the chemical reaction process. In an article, author is Ibrahim, Magdy A., once mentioned the application of 132-64-9, Name is Dibenzo[b,d]furan, molecular formula is C12H8O. Now introduce a scientific discovery about this category, Application In Synthesis of Dibenzo[b,d]furan.
A novel series of heterocyclic systems fused coumarins and chromones were efficiently synthesized from chemical transformations of 6,8-dimethylchromone-3-carbonitrile (1) with a variety of carbon nucleophilic reagents. Ring opening ring closure reactions of carbonitrile 1 with cyanoacetohydrazide, malononitrile dimer (2-aminoprop-1-ene-1,1,3-tricarbonitrile), and isomeric cyclohexanediones led to a diversity of coumarins and chromones fused nitrogen heterocyclic systems. Also, 1-ethyl-4-hydroxyquinolin-2(1H)-one (13) and 6-ethyl-4-hydroxypyrano[3,2-c]quinoline-2,5(6H)-dione (14) are chemical equivalent towards carbonitrile 1 leading to benzo [h]chromeno[2,3-b][1, 6] naphthyridine derivative 15. Structures of the new synthesized products were deduced on the basis of their analytical and spectral data.
The potential utility of systematic synthetic strategy will be applicable to efficient generations of chemical libraries of compounds to find ‘hit’ molecules. I hope my blog about 132-64-9 is helpful to your research. Application In Synthesis of Dibenzo[b,d]furan.
Reference:
1,8-Naphthyridine – Wikipedia,
,1,8-Naphthyridine | C8H6N2 – PubChem