Chemistry graduates have much scope to use their knowledge in a range of research sectors, including roles within chemical engineering, chemical and related industries, healthcare and more. 63503-60-6, Name is 3-Chlorophenylboronic acid, molecular formula is C6H6BClO2, Name: 3-Chlorophenylboronic acid, SMILES is ClC1=CC=CC(=C1)B(O)O belongs to naphthyridine compound, is a common compound. In a patnet, author is Grzegozek, M, once mentioned the new application about 63503-60-6.
3-Nitro-1,5-naphthyridine and its 2-substituted derivatives (1a-f) are dehydro-methy laminated with a solution of potassium permanganate in liquid methylamine (LMA-PP) to the corresponding 4-methylamino-3-nitro-1,5-naphthyridines (3a-e). The intermediary 4-methylamino sigma adducts of 2-R-3-nitro-1,5-naphthyridines (R = H, NH2, Cl, NHCH3, OC2H5, OH) (2a-f) are detected by H-1 nmr spectroscopy. The observed highly regioselective course of study reactions was confirmed by PM3 quantum chemical calculations of the reaction pathway. The calculations show satisfactory agreement between calculated and observed results. A convenient synthesis of 2-hydroxy- and 4-methylamino-3-nitro-1,5-naphthyridine are reported.
Future efforts will undeniably focus on the diversification of the new catalytic transformations. In my other articles, you can also check out more blogs about 63503-60-6. Name: 3-Chlorophenylboronic acid.
Reference:
1,8-Naphthyridine – Wikipedia,
,1,8-Naphthyridine | C8H6N2 – PubChem