The dynamic chemical diversity of the numerous elements, ions and molecules that constitute the basis of life provides wide challenges and opportunities for research. In an article, author is Ahmed, N. S., once mentioned the application of 1588-83-6, Name is 4-Amino-3-nitrobenzoic acid. Now introduce a scientific discovery about this category, SDS of cas: 1588-83-6.
Novel pyrazole derivatives 3a,b, 5, 1,3,4-oxadiazole 6, 1,3,4-thiadiazole 8, and 1,2,4-triazole 9a-c incorporated into 1,8-naphthyridine have been synthesized using the versatile synthon 2-(2,7-dimethyl-1,8-naphthyridin-4-yloxy) acetohydrazide 1. An improvement in rates and yields was observed when the reactions were carried out under ultrasonic irradiation compared with the classical synthesis. The newly synthesized compounds were evaluated for HepG2 cell growth inhibition. The results obtained revealed that the tested compounds possess inhibitory effect on the growth of HepG2 liver cancer cells. The results were compared to doxorubicin (DOX) as a reference drug (IC50 : 0.04 M). Compounds 9b showed the highest inhibition activity against HepG2 cell line (IC50 : 0.048 M) among all tested compounds.
Therefore, this conceptually novel strategy might open impressive avenues to establish green and sustainable chemistry platforms. If you like, you can also browse other articles about this kind. Thanks for taking the time to read the blog about 1588-83-6, SDS of cas: 1588-83-6.
Reference:
1,8-Naphthyridine – Wikipedia,
,1,8-Naphthyridine | C8H6N2 – PubChem