New Advances in Chemical Research in 2021. In an article, author is Matsumoto, Saki, once mentioned the application of 573-17-1, Name is 9-Bromophenanthrene, molecular formula is C14H9Br, molecular weight is 257.13, category is naphthyridine. Now introduce a scientific discovery about this category, HPLC of Formula: https://www.ambeed.com/products/573-17-1.html.
Programmed -1 ribosomal frameshifting (-1PRF) is a recoding mechanism to make alternative proteins from a single mRNA transcript. -1PRF is stimulated by cis-acting signals in mRNA, a seven-nucleotide slippery sequence and a downstream secondary structure element, which is often a pseudoknot. In this study we engineered the frameshifting pseudoknot from the mouse mammary tumor virus to respond to a rationally designed small molecule naphthyridine carbamate tetramer (NCTn). We demonstrate that NCTn can stabilize the pseudoknot structure in mRNA and activate -1PRF both in vitro and in human cells. The results illustrate how NCTn-inducible -1PRF may serve as an important component of the synthetic biology toolbox for the precise control of gene expression using small synthetic molecules.
The prevalence of solvent effects in heterogeneous catalysis in condensed media has motivated developing quantitative kinetic, their interactions with reaction intermediates and transition states. I hope my blog about 573-17-1 is helpful to your research. HPLC of Formula: https://www.ambeed.com/products/573-17-1.html.
Reference:
1,8-Naphthyridine – Wikipedia,
,1,8-Naphthyridine | C8H6N2 – PubChem