New Advances in Chemical Research, April 2021.The transformation of simple hydrocarbons into more complex has revolutionised modern synthetic chemistry. This type of reactivity has quickly become one of the cornerstones of modern catalysis .13331-27-6, Name is 3-Nitrophenylboronic acid, SMILES is C1=C(C=CC=C1[N+]([O-])=O)B(O)O, belongs to naphthyridine compound. In a document, author is Bardasov, Ivan N., introduce the new discover, Safety of 3-Nitrophenylboronic acid.
The one-pot reaction of aromatic aldehydes, malononitrile dimer, and triethylamine unexpectedly led to ammonium salts of not previously assumed 5,7-diamino-4-aryl-2-(dicyanomethyl)-1,4-dihydro-1,8-naphthyridine-3,6-dicarbonitriles, but the isomeric 5,7-diamino-4-aryl-2-(dicyanomethyl)-1,4-dihydro-1,6-naphthyridine-3,8-dicarbonitriles. Following neutralization and dehydrogenation led to the new, annulated with pyridine ring tricyanopyridines (TCPy).
The result showed that such a combination of chemo- and biocatalysis improved the catalytic yield more than two times compared with that of sole metal catalysis.Welcome to check out more blogs about 13331-27-6, in my other articles. Safety of 3-Nitrophenylboronic acid.
Reference:
1,8-Naphthyridine – Wikipedia,
,1,8-Naphthyridine | C8H6N2 – PubChem