Chemistry is traditionally divided into organic and inorganic chemistry. The former is the study of compounds containing at least one carbon-hydrogen bonds. 92-70-6, Name is 3-Hydroxy-2-naphthoic acid, molecular formula is C11H8O3, belongs to naphthyridine compound, is a common compound. In a patnet, author is Lu, Yihuan, once mentioned the new application about 92-70-6, Name: 3-Hydroxy-2-naphthoic acid.
A novel naphthyridine tetramer that recognizes tandem G-G mismatches by the formation of an interhelical complex
We have designed and synthesized a novel naphthyridine tetramer, p-NCTB, for the recognition of tandem guanine-guanine (G-G) mismatches in DNA. p-NCTB possesses a p-biphenyl linker connecting two naphthyridine carbamate dimer (NCD) moieties that recognize G-G mismatches. p-NCTB preferentially bound to tandem G-G mismatches in dCGGG/dCGGG over dCGG/dCGG. Two dCGGG/dCGGG sites were simultaneously recognized and were noncovalently cross-linked via the formation of inter- and intrastrand complexes with p-NCTB. The intrastrand binding was more favorable, which could allow p-NCTB to bind selectively to a sequence containing multiple dCGGG/dCGGG sites.
We’ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, 92-70-6. The above is the message from the blog manager. Name: 3-Hydroxy-2-naphthoic acid.
Reference:
1,8-Naphthyridine – Wikipedia,
,1,8-Naphthyridine | C8H6N2 – PubChem