Chemistry, like all the natural sciences, begins with the direct observation of nature¡ª in this case, of matter.96-49-1, Name is Ethylene carbonate, SMILES is O=C1OCCO1, belongs to naphthyridines compound. In a document, author is Suryawanshi, M. R., introduce the new discover, Recommanded Product: Ethylene carbonate.
SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF SOME COMPOUNDS OF 1,8-NAPHTHYRIDINE-3-CARBOXAMIDE
Various nitrogenous heterocyclic compounds like 1, 8-naphthyridine-3-carboxamide are synthesized and studied for their wide range of biological activity. Versatile activity of this scaffold will increase interest from innovator on significance of their antibacterial activity and will influence their role in drug discovery. Synthesis and Antibacterial evaluation of ten derivatives of 1-ethyl-4-oxo-1, 4-dihydro-1, 8-naphthyridine-3-carboxamide (SD-1 – SD10) is discussed in this paper. Synthesis of novel 1, 8-naphthyridine-3-carboxamide derivatives starting from substituted pyridine with ethoxymethylenemalonate ester by cyclo-condensation reaction affords 1,8-Napthyridine-3-carboxylate at high temperature and at specific reaction condition. All 1, 8-napthyridine-3-carboxylate compounds were treated with an excess of substituted aniline with mild reaction conditions. All the compounds obtained were purified by using the recrystallization method. Structure confirmation of synthesized compounds was accomplished on the basis of IR, H-1 NMR, and MS. The synthesized compounds were tested against bacterial strain, Escherichia coli (Gram-negative) Staphylococcus aureus (Gram-positive). Many of the compounds exhibited significant antibacterial profile.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 96-49-1 is helpful to your research. Recommanded Product: Ethylene carbonate.
Reference:
1,8-Naphthyridine – Wikipedia,
,1,8-Naphthyridine | C8H6N2 – PubChem