In an article, author is Dyubankova, N., once mentioned the application of 620-92-8, Name: 4,4′-Methylenediphenol, Name is 4,4′-Methylenediphenol, molecular formula is C13H12O2, molecular weight is 200.23, MDL number is MFCD00002385, category is naphthyridines. Now introduce a scientific discovery about this category.
NMR study on the interaction of the conserved CREX ‘stem-loop’ in the Hepatitis E virus genome with a naphthyridine-based ligand
A 2-amino-1,8-naphthyridine derivative that is described to bind single guanine bulges in RNA-DNA and RNA-RNA duplexes was synthesized and its interaction with the single G bulge in the conserved CREX of the Hepatitis E Virus (HEV) genome was explored by NMR and molecular modeling. Results indicate that the ligand intercalates in the internal loop, though none of the expected hydrogen bonds with the single G in the bulge could be demonstrated.
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Reference:
1,8-Naphthyridine – Wikipedia,
,1,8-Naphthyridine | C8H6N2 – PubChem