Children learn through play, and they learn more than adults might expect. Science experiments are a great way to spark their curiosity, Name: N-Cyclohexylmaleimide1631-25-0, Name is N-Cyclohexylmaleimide, SMILES is O=C(C=C1)N(C2CCCCC2)C1=O, belongs to naphthyridines compound. In a article, author is Yu, Shasha, introduce new discover of the category.
Zirconium-Mediated Multicomponent Reactions of 1,3-Butadiynes with Ylidenemalononitriles to Form Functionalized 1,8-Naphthyridine and Cyclopenta[b]pyridine Derivatives
Zirconocene-mediated multicomponent reactions of 1,3-butadiynes with ylidenemalononitriles in the absence or presence of CuCl have been developed. In the absence of CuCl, 1,3-butadiyne couples with three molecules of ylidenemalononitriles to yield azazirconacycles bearing a hexahydro-1,8-naphthyridine skeleton with high stereoselectivity. In the presence of CuCl, cyclopenta[b]pyridine or cyclopenta[b] quinolin-1-one derivatives are obtained via transmetalation of Zr-C bond to Cu-C bond as the key reaction step. These domino-type reactions proceed with high chemo-, regio- and/or stereoselectivities, and allowing the formation of multiple C-N and C-C bonds in a single operation.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 1631-25-0. Name: N-Cyclohexylmaleimide.
Reference:
1,8-Naphthyridine – Wikipedia,
,1,8-Naphthyridine | C8H6N2 – PubChem