Chemistry, like all the natural sciences, Computed Properties of C7H6N2O4, begins with the direct observation of nature¡ª in this case, of matter.1588-83-6, Name is 4-Amino-3-nitrobenzoic acid, SMILES is C1=C([N+]([O-])=O)C(=CC=C1C(=O)O)N, belongs to naphthyridines compound. In a document, author is Park, T, introduce the new discover.
A quadruply hydrogen bonded heterocomplex displaying high-fidelity recognition
An exceptionally strong quadruply hydrogen-bonded complex is formed between 2,7-diamido-1,8-naphthyridine 3 (DAN) and the butylurea of guanosine 6 (UG) in chloroform. The UG unit can be prepared in four steps from guanosine on a 10 g scale in excellent yields without chromatographic purification. The association constant (K-assoc approximate to 5 x 10(7) m(-1)) for the UG(.)DAN complex determined by fluorescence energy transfer from the naphthyridine unit of 3 to coumarin 343 covalently linked UG (18) is among the highest reported for a neutral DNA base-pair analogue. The weak self-association of DAN (K-dimer < 10 m(-1)) and UG (K-dimer ca. 200-300 m(-1)) means that the UG-DAN complex forms with unparalleled fidelity. Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 1588-83-6. Computed Properties of C7H6N2O4.
Reference:
1,8-Naphthyridine – Wikipedia,
,1,8-Naphthyridine | C8H6N2 – PubChem