Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 298-96-4, Name is Tetrazolium Red, molecular formula is C19H15ClN4, belongs to naphthyridines compound. In a document, author is Al-romaizan, Abeer N., introduce the new discover, Application In Synthesis of Tetrazolium Red.
Novel 1,8-Naphthyridine Derivatives: Design, Synthesis and in vitro screening of their cytotoxic activity against MCF7 cell line
A series of new 2-phenyl-7-methyl-1,8-naphthyridine derivatives with variable substituents at C3 were synthesized for an in vitro evaluation of their anticancer activity against human breast cancer cell line (MCF7). On one hand, compounds 3f, 6f, 8c, and 10b showed IC50 values (6.53, 7.88, 7.89, 7.79 mu M, respectively) compared to that of the mentioned drug staurosparine (IC50 = 4.51 mu M). On the other hand, derivatives 10c, 8d, 4d, 10f and 8b displayed better activity than staurosporin with IC50 values (1.47, 1.62, 1.68, 2.30, 3.19 mu M, respectively).
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law. In my other articles, you can also check out more blogs about 298-96-4. Application In Synthesis of Tetrazolium Red.
Reference:
1,8-Naphthyridine – Wikipedia,
,1,8-Naphthyridine | C8H6N2 – PubChem