Reference of 709-63-7, Catalysts allow a reaction to proceed via a pathway that has a lower activation energy than the uncatalyzed reaction. 709-63-7, Name is 4-(Trifluoromethyl)acetophenone, SMILES is C1=C(C=CC(=C1)C(C)=O)C(F)(F)F, belongs to naphthyridines compound. In a article, author is Reddy, Puchakayala Bharath Kumar, introduce new discover of the category.
Intramolecular Heck reaction: A facile sequential one-pot synthesis of 1,2,3,4-tetrahydrobenzo[b][1,6]naphthyridines
A simple and convenient sequential one-pot synthesis of 1,2,3,4-tetrahydrobenzo[b][1,6] naphthyridines has been developed. The reductive amination of 2-chloro-3-formylquinolines with various amines in the presence of sodium borohydride provided the corresponding secondary amines in high yields. Further, a sequential one-pot reaction involving N-allylation and intramolecular Heck type 6-exo-trig cyclization was performed on the secondary amines to afford a range of desired 1,2,3,4-tetrahydrobenzo[b][1,6]naphthyridine derivatives in good to high yields. (C) 2018 Elsevier Ltd. All rights reserved.
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Reference:
1,8-Naphthyridine – Wikipedia,
,1,8-Naphthyridine | C8H6N2 – PubChem