Chemistry can be defined as the study of matter and the changes it undergoes. You¡¯ll sometimes hear it called the central science because it is the connection between physics and all the other sciences, starting with biology. 573-17-1, Name is 9-Bromophenanthrene, molecular formula is , belongs to naphthyridines compound. In a document, author is Maity, Arnab K., Recommanded Product: 9-Bromophenanthrene.
A Dinickel Catalyzed Cyclopropanation without the Formation of a Metal Carbene Intermediate
(NDI)Ni-2 catalysts (NDI=naphthyridine-diimine) promote cyclopropanation reactions of 1,3-dienes using (Me3Si)CHN2. Mechanistic studies reveal that a metal carbene intermediate is not part of the catalytic cycle. The (NDI)Ni-2(CHSiMe3) complex was independently synthesized and found to be unreactive toward dienes. Based on DFT models, we propose an alternative mechanism that begins with a Ni-2-mediated coupling of (Me3Si)CHN2 and the diene. N-2 extrusion followed by radical C-C bond formation generates the cyclopropane product. This model reproduces the experimentally observed regioselectivity and diastereoselectivity of the reaction.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 573-17-1, in my other articles. Recommanded Product: 9-Bromophenanthrene.
Reference:
1,8-Naphthyridine – Wikipedia,
,1,8-Naphthyridine | C8H6N2 – PubChem