Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 1588-83-6, Name is 4-Amino-3-nitrobenzoic acid, SMILES is C1=C([N+]([O-])=O)C(=CC=C1C(=O)O)N, belongs to naphthyridines compound. In a document, author is Huang, Shengdian, introduce the new discover, Safety of 4-Amino-3-nitrobenzoic acid.
Design and synthesis of imidazo[1,2-alpha][1,8]naphthyridine derivatives as anti-HCV agents via direct C-H arylation
RO8191 represents a newly identified small-molecule IFN-alpha-substitute, which displays potent anti-HCV activity. In this communication, we reported the design and synthesis of two series of imidazo[1,2-alpha][1,8]naphthyridine derivatives, as RO8191 analogues, via a direct C-H arylation approach. Notably, by adjusting the reaction conditions, we could achieve the two series of analogues via regioselective single-and double-arylations, respectively. The anti-HCV activities of the synthesized compounds were evaluated within the HCV cell culture system, and the preliminary results showed that some of them displayed promising anti-HCV activities.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 1588-83-6 is helpful to your research. Safety of 4-Amino-3-nitrobenzoic acid.
Reference:
1,8-Naphthyridine – Wikipedia,
,1,8-Naphthyridine | C8H6N2 – PubChem