Quantitative correlation between the electronic structure and diuretic activity of azanaphthalene derivatives was written by Singh, P.;Gupta, S. P.. And the article was included in Indian Journal of Medical Research (1913-1988) in 1979.Quality Control of 2,6-Naphthyridine This article mentions the following:
A mol. orbital PPP method was used to study the relationship between the electronic structure and the diuretic activity of azanaphthalene derivatives Regression anal. revealed significant linear correlation between the charge d. at the ring junction and the diuretic activity of the compounds In the experiment, the researchers used many compounds, for example, 2,6-Naphthyridine (cas: 253-50-9Quality Control of 2,6-Naphthyridine).
2,6-Naphthyridine (cas: 253-50-9) belongs to naphthyridine derivatives. Functionalized naphthyridines and their benzo/heterofused analogs are present in numerous marine products and reported to possess wide-ranging activities such as antiproliferative, antiaggressive, and HIV-1 integrase inhibition in addition to their use as anti-HCV agents. Transition metal complexes of 1,5-naphthyridine (1,5-napy) seems to form one-dimensional coordination polymers with the ligand acting as bidentate in a “stepped” bridging fashion.Quality Control of 2,6-Naphthyridine
Referemce:
1,8-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N2 – PubChem