Month: December 2022

Han, Yi published the artcileFormation of Azulene-Embedded Nanographene: Naphthalene to Azulene Rearrangement During the Scholl Reaction, Synthetic Route of 152873-79-5, the publication is Angewandte Chemie, International Edition (2020), 59(23), 9026-9031, database is CAplus and MEDLINE.

Incorporation of a non-hexagonal ring into a nanographene framework can lead to new electronic properties. During the attempted synthesis of naphthalene-bridged double [6]helicene and heptagon-containing nanographene by the Scholl reaction, an unexpected azulene-embedded nanographene and its triflyloxylated product were obtained, as confirmed by X-ray crystallog. anal. and 2D NMR spectroscopy. A 5/7/7/5 ring-fused substructure containing two formal azulene units is formed, but only one of them shows an azulene-like electronic structure. The formation of this unique structure is explained by arenium ion mediated 1,2-Ph migration and a naphthalene to azulene rearrangement reaction according to an in-silico study. This report represents the first exptl. example of the thermodynamically unfavorable naphthalene to azulene rearrangement and may lead to new azulene-based mol. materials.

Angewandte Chemie, International Edition published new progress about 152873-79-5. 152873-79-5 belongs to naphthyridine, auxiliary class Trifluoromethyl,Sulfonate,Benzene, name is 1,5-NAphthalenebis(trifluoromethanesulfonate), and the molecular formula is C12H6F6O6S2, Synthetic Route of 152873-79-5.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Sun, Mingli published the artcileToward Eco-friendly Green Organic Semiconductors: Recent Advances in Spiro[fluorene-9,9′-xanthene] (SFX)-Based Optoelectronic Materials and Devices, HPLC of Formula: 159-62-6, the publication is Chinese Journal of Chemistry (2015), 33(8), 815-827, database is CAplus.

A review. Green organic semiconductors (GOS) have the four-element features, including biomass as stuffs, synthesis with the pot, atom and step economic (PASE) route, eco-friendly fabrication processes in aqueous phase, and recyclable devices, capturing the trend of organic electronics in the future. Herein, we reviewed the efforts that have been made on GOS by our group. We first made a brief introduction of organic (opto)electronics, followed by the design strategies of GOSs based on spirofluorenes. Concretely, we described the discovery of one-pot protocol to spirofluorenres and a pot-atom-step economic (PASE) platform of spiro[fluorene-9,9′-xanthene] (SFX) for the mol. design of organic semiconductors, as well as a state-of-the-art nanocrystalline films with eco-friendly procedures. Then, we highlighted the progress on SFX-based organic semiconductors in the organic light-emitting diode (OLED) field. Finally, we conducted a summary on SFXs in OLED and an outlook on green semiconductors starting from biomass, via one-pot to spirofluorenes, to water-phase devices.

Chinese Journal of Chemistry published new progress about 159-62-6. 159-62-6 belongs to naphthyridine, auxiliary class Other Aromatic Heterocyclic,Spiro, name is Spiro[fluorene-9,9′-xanthene], and the molecular formula is C9H9NO6S, HPLC of Formula: 159-62-6.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Wang, Jin published the artcileExcellent charge-storage properties of polystyrene/SFXs electret films by repeated contact with an AFM probe, Recommanded Product: Spiro[fluorene-9,9′-xanthene], the publication is Physica Status Solidi B: Basic Solid State Physics (2018), 255(6), n/a, database is CAplus.

The stability of charges trapped by the single-contact and repeated-contact modes with at. force microscopy (AFM) probe for polystyrene/cruciformed spiro [fluorene-9,9′-xanthene] (PS/SFXs) electret films is detected by Kelvin probe force microscopy (KPFM). The influences of the contact duration and number of contacts on the trapped charges are explored. We found that the contact duration and number of contacts are important factors to improve the trapping property. The repeated contacts between the AFM probe and the sample are a promising way to improve the stability of trapped charges in PS/SFXs. The possible mechanisms for improving storage properties are also discussed.

Physica Status Solidi B: Basic Solid State Physics published new progress about 159-62-6. 159-62-6 belongs to naphthyridine, auxiliary class Other Aromatic Heterocyclic,Spiro, name is Spiro[fluorene-9,9′-xanthene], and the molecular formula is C15H15OP, Recommanded Product: Spiro[fluorene-9,9′-xanthene].

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Zhang, Jinbao published the artcileThe Importance of Pendant Groups on Triphenylamine-Based Hole Transport Materials for Obtaining Perovskite Solar Cells with over 20% Efficiency, Product Details of C25H16O, the publication is Advanced Energy Materials (2018), 8(2), n/a, database is CAplus.

Tremendous progress has recently been achieved in the field of perovskite solar cells (PSCs) as evidenced by impressive power conversion efficiencies (PCEs); but the high PCEs of >20% in PSCs has so far been mostly achieved by using the hole transport material (HTM) spiro-OMeTAD; however, the relatively low conductivity and high cost of spiro-OMeTAD significantly limit its potential use in large-scale applications. In this work, two new organic mols. with spiro[fluorene-9,9′-xanthene] (SFX)-based pendant groups, X26 and X36, have been developed as HTMs. Both X26 and X36 present facile syntheses with high yields. It is found that the introduced SFX pendant groups in triphenylamine-based mols. show significant influence on the conductivity, energy levels, and thin-film surface morphol. The use of X26 as HTM in PSCs yields a remarkable PCE of 20.2%. In addition, the X26-based devices show impressive stability maintaining a high PCE of 18.8% after 5 mo of aging in controlled (20%) humidity in the dark. We believe that X26 with high device PCEs of >20% and simple synthesis show a great promise for future application in PSCs, and that it represents a useful design platform for designing new charge transport materials for optoelectronic applications.

Advanced Energy Materials published new progress about 159-62-6. 159-62-6 belongs to naphthyridine, auxiliary class Other Aromatic Heterocyclic,Spiro, name is Spiro[fluorene-9,9′-xanthene], and the molecular formula is C8H6ClF3, Product Details of C25H16O.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Bi, Dongqin published the artcileFacile synthesized organic hole transporting material for perovskite solar cell with efficiency of 19.8%, COA of Formula: C25H16O, the publication is Nano Energy (2016), 138-144, database is CAplus.

The exploration of alternative mol. hole-transporting materials (HTMs) specifically for high performance perovskite solar cells (PSCs) is a relatively recent research area. Aiming for further increasing the ‘efficiency-cost ratio’ of PSCs, we developed a spiro[fluorene-9,9′-xanthene] based HTM (X59) via two-step synthesis from com. precursors for perovskite solar cells (PSCs) that works as effectively as the well-known HTM-Spiro-OMeTAD-based device under the same conditions. The mol. structure was analyzed by X-ray crystallog. indicating a similar packing regime as for Spiro-OMeTAD. An impressive PCE of 19.8% was achieved by using X59 as HTM in PSC, which can compete with the record PCE of 20.8% by using the state-of-the-art-HTM Spiro-OMeTAD (Tress et al., 2016) [1]. The optimized devices employing X59 as HTM exhibited minimized hysteresis, excellent reproducibility and reasonable stability under dark and dry conditions. The present finding highlights the potential of spiro-type HTM for high performance PSCs and paves the way to a much deceased fabrication cost for potential commercialization of perovskite solar panels.

Nano Energy published new progress about 159-62-6. 159-62-6 belongs to naphthyridine, auxiliary class Other Aromatic Heterocyclic,Spiro, name is Spiro[fluorene-9,9′-xanthene], and the molecular formula is C25H16O, COA of Formula: C25H16O.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Deguchi, Atsuko published the artcileActivation of Protein Kinase G Up-regulates Expression of 15-Lipoxygenase-1 in Human Colon Cancer Cells, Category: naphthyridine, the publication is Cancer Research (2005), 65(18), 8442-8447, database is CAplus and MEDLINE.

Recent studies indicate that the induction of apoptosis in human colon cancer cells by certain nonsteroidal anti-inflammatory drugs involves increased expression of 15-LOX-1 and synthesis of its major product 13-S-hydroxyoctadecadienoic acid (13-S-HODE). Evidence was obtained that this occurs via a cyclooxygenase-2 (COX-2)-independent mechanism, but the actual mechanism of induction of 15-LOX-1 by these compounds is not known. There is extensive evidence that treatment of SW480 human colon cancer cells with sulindac sulfone (Exisulind, Aptosyn) or the related derivative OSI-461, both of which inhibit cGMP-phosphodiesterases but lack COX-2 inhibitory activity, causes an increase in intracellular levels of cGMP, thus activating protein kinase G (PKG), which then activates pathways that lead to apoptosis. Therefore, in the present study, the authors examined the effects of various agents that cause increased cellular levels of cGMP on the expression of 15-LOX-1 in SW480 human colon cancer cells. Treatment of the cells with Exisulind, sulindac sulfide, OSI-461, the guanylyl cyclase activator YC-1, or the cell-permeable cGMP compound 8-para-chlorophenylthio-cGMP (8-pCPT-cGMP) caused an increase in cellular levels of 15-LOX-1. Exisulind, OSI-461, and 8-pCPT-cGMP also increased mRNA levels of 15-LOX-1, suggesting that the effects were at the level of transcription. The cGMP-phosphodiesterase inhibitors and YC-1 increased the production of 13-S-HODE, which is the linoleic acid metabolite of 15-LOX-1. Treatment of SW480 cells with the PKG inhibitor R_p-8-pCPT-cGMP blocked Exisulind-induced 15-LOX-1 expression. Furthermore, derivatives of SW480 cells that were engineered to stably overexpress wild-type PKG Iβ displayed increased cellular levels of 15-LOX-1 when compared with vector control cells. Taken together, these results provide evidence that the cGMP/PKG pathway can play an important role in the induction of 15-LOX-1 expression by nonsteroidal anti-inflammatory drugs and related agents.

Cancer Research published new progress about 59973-80-7. 59973-80-7 belongs to naphthyridine, auxiliary class Immunology/Inflammation,COX, name is Sulindac sulfone, and the molecular formula is C20H17FO4S, Category: naphthyridine.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Liu, Guochao published the artcileAdsorptive separation of binary naphthalene compounds by D201 resin, Formula: C10H9NO4S, the publication is Huanjing Huaxue (2012), 31(3), 372-378, database is CAplus.

D201 strong-base anion exchange resins were used to selectively adsorb and sep. 1-amino-2-naphthol-4-sulfonic acid (1,2,4-acid) and 2-naphthol in binary aqueous solution The effect of pH, concentration, temperature, resin bed height, and flow rate was investigated. The results show that D201 resin had very high adsorption selectivity and adsorption capacity for 1,2,4-acid in pH 3-6. Temperature had very little influence on D201 resin adsorption of 1,2,4-acid and 2-naphthol. The adsorption isotherms of 1,2,4-acid and 2-naphthol on the resin obey Freundlich model. Dynamic adsorption of the mixed aqueous 1,2,4-acid and 2-naphthol solution by D201 resin shows that, to the leak point of 1,2,4-acid, the adsorption effluent contained essentially 2-naphthol only, and 1,2,4-acid was completely adsorbed by the resin. With the increase of the resin bed and the decreases of the initial concentration and flow rate, the leak point was prolonged and the separation coefficient of 1,2,4-acid for 2-naphthol was improved. 1,2,4-Acid adsorbed on the column was eluted quant. by 15% (weight) NH₄Cl and 20% (volume) ethanol solution

Huanjing Huaxue published new progress about 116-63-2. 116-63-2 belongs to naphthyridine, auxiliary class Sulfonic acid,Amine,Naphthalene,Alcohol,Organic Pigment, name is 4-Amino-3-hydroxynaphthalene-1-sulfonic acid, and the molecular formula is C10H9NO4S, Formula: C10H9NO4S.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Zheng, Yu published the artcilePhosphonium Ylide-Mediated Programmable Fluorination to Access Mono- and Difluoromethylarenes, Application In Synthesis of 53731-26-3, the publication is Organic Letters, database is CAplus and MEDLINE.

Compounds bearing fluorinated moieties are pervasive in a wide range of pharmaceuticals and agrochems. The installation of fluorinated units is a persistently vital task in synthetic chem., where facile and manipulable assays are highly demanding. Herein, we establish a general and programmable fluorination strategy for the modular assembly of mono- and difluoromethylarenes through the controllable deprotonation and fluorination of phosphonium ylides. Moreover, the rational combination of the reaction sequence allows the rapid construction of diversified fluorine-containing arenes.

Organic Letters published new progress about 53731-26-3. 53731-26-3 belongs to naphthyridine, auxiliary class Difluoromethyl,Fluoride,Naphthalene, name is 1-(Difluoromethyl)naphthalene, and the molecular formula is C23H20BN, Application In Synthesis of 53731-26-3.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

He, Guowen published the artcilePh₂S/selectfluor-promoted deoxydifluorination of aldehydes, COA of Formula: C11H8F2, the publication is Tetrahedron (2021), 131963, database is CAplus.

The installation of a HCF₂ group is a research area that has received increasing attention, and deoxydifluorination of aldehydes have served as an attractive protocol due to the wide availability of aldehydes. Herein a Ph₂S/selectfluor-promoted deoxydifluorination of aldehydes under mild conditions is described. Compared with previous deoxydifluorination methods, which usually use hazardous reagents such as SF₄, DAST and deoxo-fluor, this protocol is quite attractive because of the safe and convenient operations, and the use of easily available reagents.

Tetrahedron published new progress about 53731-26-3. 53731-26-3 belongs to naphthyridine, auxiliary class Difluoromethyl,Fluoride,Naphthalene, name is 1-(Difluoromethyl)naphthalene, and the molecular formula is C11H8F2, COA of Formula: C11H8F2.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Yuan, Jin-hai published the artcileTreatment of 1,2,4-acid wastewater by ferric-carbon microelectrolysis combined with Fenton oxidation process, Name: 4-Amino-3-hydroxynaphthalene-1-sulfonic acid, the publication is Chongqing Daxue Xuebao, Ziran Kexueban (2011), 34(9), 121-127, database is CAplus.

Experiments on the treatment process of 1,2,4-acid wastewater combined ferric-carbon microelectrolysis with Fenton oxidation process are carried out. The 1,2,4-acid wastewater is produced in the production process of 6-nitry (6-nitro-1-diazo oxygen naphthalene-4-acid). The exptl. conditions of Ferric-Carbon microelectrolysis, including pH value, reaction time, reaction temperature, Fe/C ratio and dosage of active carbon are studied. Fenton oxidation conditions of pH value, dosage of H₂O₂ and the economy data of the process are analyzed. Through single-factor experiments, the conditions for treating acid wastewater are found out. PH value is 1, Fe and C mass ratio is 3:1, and iron-carbon microelectrolysis reaction time is 3 h. The iron-carbon micro-electrolysis water is filtered to adjust its pH value into 3, then 2.5% wastewater of H₂O₂ with mass fraction of 30% is added, a reaction is performed at room temperature for 1 h, the pH value is adjusted into 7∼8, and then the iron-carbon micro-electrolysis water is filtered. The removal efficiency of COD of raw water can be improved to more than 95%. The cost of wastewater treating is 5.4 yuan/m³.

Chongqing Daxue Xuebao, Ziran Kexueban published new progress about 116-63-2. 116-63-2 belongs to naphthyridine, auxiliary class Sulfonic acid,Amine,Naphthalene,Alcohol,Organic Pigment, name is 4-Amino-3-hydroxynaphthalene-1-sulfonic acid, and the molecular formula is C6H8O4, Name: 4-Amino-3-hydroxynaphthalene-1-sulfonic acid.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem