Efficient and eco-friendly synthesis of 1,7-naphthyridines was written by Srivastava, K. P.;Indu, Singh;Anupma, Kumari. And the article was included in International Journal of Chemical and Physical Sciences in 2014.Name: 6-Amino-8-bromo-1,7-naphthyridine This article mentions the following:
A microwave-promoted new easy, efficient, clean and environmentally benign method for the synthesis of 1,7-naphthyridine and its derivatives I [R1 = NH2; R2 = H, Br] from 2-cyano-3-pyridylacetonitrile has been developed. The desired products were isolated in excellent yields and high purity under eco-friendly conditions. In the experiment, the researchers used many compounds, for example, 6-Amino-8-bromo-1,7-naphthyridine (cas: 5912-35-6Name: 6-Amino-8-bromo-1,7-naphthyridine).
6-Amino-8-bromo-1,7-naphthyridine (cas: 5912-35-6) belongs to naphthyridine derivatives. The naphthyridine ring system, being very π-deficient, is highly vulnerable towards nucleophilic attack, and consequently there has been extensive investigation of reactions involving nitrogen nucleophiles. Enoxacin, nalidixic acid, and trovafloxacin are 1,8-naphthyridine derivatives with antibacterial properties related to the fluoroquinolones.Name: 6-Amino-8-bromo-1,7-naphthyridine
Referemce:
1,8-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N2 – PubChem