Synthesis of 4-(8-benzo[1,2,5]oxadiazol-5-yl-[1,7]naphthyridine-6-yl)-benzoic acid: a potent and selective phosphodiesterase type 4D inhibitor was written by Hersperger, Rene;Dawson, Janet;Mueller, Thomas. And the article was included in Bioorganic & Medicinal Chemistry Letters in 2002.Formula: C8H6BrN3 This article mentions the following:
The synthesis of a 6,8-disubstituted 1,7-naphthyridine and its characterization as a potent and selective phosphodiesterase type 4D inhibitor (IC50=1.5 nM) are described. The title compound, i.e., 4-[8-(2,1,3-benzoxadiazol-5-yl)-1,7-naphthyridin-6-yl]benzoic acid and 4-[8-(2,1,3-benzoxadiazol-5-yl)-1,7-naphthyridin-6-yl]benzoic acid salt with 1-deoxy-1-(methylamino)-
6-Amino-8-bromo-1,7-naphthyridine (cas: 5912-35-6) belongs to naphthyridine derivatives. Six naphthyridine isomers exist, based on the positions of the nitrogen atoms; they can be in the 1,5, 1,6, 1,7, 1,8, 2,6, or 2,7 positions. 1,6-Naphthyridine and some of its derivatives have been reported to have medicinal, electronic, and catalytic properties. But none of these investigations has yet resulted in any practical applications.Formula: C8H6BrN3
Referemce:
1,8-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N2 – PubChem