Middleton, William J.’s team published research in Journal of Organic Chemistry in 40 | CAS: 53731-26-3

Journal of Organic Chemistry published new progress about 53731-26-3. 53731-26-3 belongs to naphthyridine, auxiliary class Difluoromethyl,Fluoride,Naphthalene, name is 1-(Difluoromethyl)naphthalene, and the molecular formula is C11H8F2, Related Products of naphthyridine.

Middleton, William J. published the artcileNew fluorinating reagents. Dialkylaminosulfur fluorides, Related Products of naphthyridine, the publication is Journal of Organic Chemistry (1975), 40(5), 574-8, database is CAplus.

Trifluorides R2NSF3 (I; R = Me, Et, Me2CH; or R2N = pyrrolidino) were prepared by the reaction of R2NSiMe3 with SF4 in FCCl3 at -78°; I reacted with R21NSiMe3 to give R2NSF2NR21 (II; R, R1 = Me, Et; or R12 = piperidino). I and II were used to fluorinate alcs., aldehydes, or ketones. E.g., I (R = Et) reacted with Me2CHCH2OH in diglyme at -50 to -78° to give 49% Me2CHCH2F and 21% Me3CF. EtCHO with I (R = Et) in FCCl3 at 25° gave 80% EtCHF2. Among ∼23 other compounds fluorinated were: cyclooctanol, BzH, 1-naphthaldehyde, and menthol.

Journal of Organic Chemistry published new progress about 53731-26-3. 53731-26-3 belongs to naphthyridine, auxiliary class Difluoromethyl,Fluoride,Naphthalene, name is 1-(Difluoromethyl)naphthalene, and the molecular formula is C11H8F2, Related Products of naphthyridine.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem