Miao, Wenjun’s team published research in Journal of the American Chemical Society in 140 | CAS: 53731-26-3

Journal of the American Chemical Society published new progress about 53731-26-3. 53731-26-3 belongs to naphthyridine, auxiliary class Difluoromethyl,Fluoride,Naphthalene, name is 1-(Difluoromethyl)naphthalene, and the molecular formula is C11H8F2, Product Details of C11H8F2.

Miao, Wenjun published the artcileIron-Catalyzed Difluoromethylation of Arylzincs with Difluoromethyl 2-Pyridyl Sulfone, Product Details of C11H8F2, the publication is Journal of the American Chemical Society (2018), 140(3), 880-883, database is CAplus and MEDLINE.

In the presence of Fe(acac)3 and N,N,N’,N’-tetramethylethylenediamine, arylzinc reagents (in most cases generated in situ from aryl Grignard reagents) underwent difluoromethylation reactions with difluoromethyl 2-pyridinyl sulfone at -40° to ambient temperature to yield difluoromethylarenes. Reaction of a difluoropentenyl 2-pyridinyl sulfone with an in situ-generated diarylzinc reagent yielded an arylmethyldifluorocyclopentane, implying the involvement of radical species in the iron-catalyzed difluoromethylation; the reaction was inhibited by TEMPO, BHT, and 1,4-dinitrobenzene.

Journal of the American Chemical Society published new progress about 53731-26-3. 53731-26-3 belongs to naphthyridine, auxiliary class Difluoromethyl,Fluoride,Naphthalene, name is 1-(Difluoromethyl)naphthalene, and the molecular formula is C11H8F2, Product Details of C11H8F2.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem