Harris, Craig S. et al. published their research in Tetrahedron Letters in 2008 |CAS: 445490-78-8

The Article related to thiophenone alc mitsunobu alkylation, thiophene ether preparation, Heterocyclic Compounds (One Hetero Atom): Thiophenes and other aspects.Quality Control of tert-Butyl 7-(2-hydroxyethyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxylate

On October 6, 2008, Harris, Craig S.; Germain, Herve; Pasquet, Georges published an article.Quality Control of tert-Butyl 7-(2-hydroxyethyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxylate The title of the article was Facile preparation of thiophene C2-ethers using the Mitsunobu reaction. And the article contained the following:

The preparation of thiophene ethers generally requires forcing conditions thus limiting the choice of alkyl substituent. Herein, we report the first successful generally applicable conditions for the selective O-alkylation of 2(5H)-thiophenone. The experimental process involved the reaction of tert-Butyl 7-(2-hydroxyethyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxylate(cas: 445490-78-8).Quality Control of tert-Butyl 7-(2-hydroxyethyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxylate

The Article related to thiophenone alc mitsunobu alkylation, thiophene ether preparation, Heterocyclic Compounds (One Hetero Atom): Thiophenes and other aspects.Quality Control of tert-Butyl 7-(2-hydroxyethyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxylate

Referemce:
1,8-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N2 – PubChem