Zhang, Ao; Ding, Chunyong; Cheng, Chen; Yao, Qizheng published their research in Journal of Combinatorial Chemistry on December 31 ,2007. The article was titled 《Convenient Synthesis of 2,7-Naphthyridine Lophocladines A and B and their Analogues》.Safety of 2,7-Naphthyridin-1-amine The article contains the following contents:
The authors developed a convenient and flexible synthetic route to lophocladines A and B, I and II, resp., as well as their C-4 substituted analogs through a regioselective bromination/iodination of 2,7-naphthyridines followed by a Suzuki, Stille, or Sonogashira reaction. This method is useful for generating a 2,7-naphthyridine library (25 members) with a variant C-4 substituent, including differently substituted aryl, heteroaryl, as well as vinyl, alkyl, and substituted or nonsubstituted acetylenyl groups.2,7-Naphthyridin-1-amine(cas: 27225-00-9Safety of 2,7-Naphthyridin-1-amine) was used in this study.
2,7-Naphthyridin-1-amine(cas: 27225-00-9) belongs to naphthyridines. Functionalized naphthyridines and their benzo/heterofused analogs are present in numerous marine products and reported to possess wide-ranging activities such as antiproliferative , antiaggressive, and HIV-1 integrase inhibition in addition to their use as anti-HCV agents .Safety of 2,7-Naphthyridin-1-amine
Referemce:
1,8-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N2 – PubChem