The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: 6-Hydroxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid, is researched, Molecular C10H11NO3, CAS is 91523-50-1, about Chemo-enzymatic synthesis of (S)-1,2,3,4-tetrahydroisoquinoline carboxylic acids using D-amino acid oxidase, the main research direction is tetrahydroisoquinoline carboxylic acid FsDAAO catalyst enantioselective enzymic resolution; chiral tetrahydroisoquinoline carboxylic acid preparation.Application In Synthesis of 6-Hydroxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid.
In this context, an (R)-selective D-amino acid oxidase from Fusarium solani M-0718 (FsDAAO) with broad substrate scope and excellent enantioselectivity was found through genome mining. This enzyme was applied for the kinetic resolution of a range of racemic 1- and 3-carboxyl substituted THIQs with different substitutions on the aryl rings. Preparative-scale deracemization of racemic 1,2,3,4- tetrahydroisoquinoline-1-carboxylic acid and 1,2,3,4-tetrahydroisoquinoline-3- carboxylic acid was further demonstrated.
After consulting a lot of data, we found that this compound(91523-50-1)Application In Synthesis of 6-Hydroxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid can be used in many types of reactions. And in most cases, this compound has more advantages.
Reference:
1,8-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N2 – PubChem