The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: (1-Isobutyl-1H-pyrazol-5-yl)boronic acid( cas:847818-64-8 ) is researched.Related Products of 847818-64-8.Kudo, Noriaki; Perseghini, Mauro; Fu, Gregory C. published the article 《A versatile method for Suzuki cross-coupling reactions of nitrogen heterocycles》 about this compound( cas:847818-64-8 ) in Angewandte Chemie, International Edition. Keywords: heteroaryl halide heteroarylboronic acid Suzuki cross coupling palladium; heteroarylboronic acid aryl halide Suzuki cross coupling palladium; nitrogen heterocycle preparation; pyridine aryl derivative preparation; palladium Suzuki cross coupling catalyst. Let’s learn more about this compound (cas:847818-64-8).
A wide-ranging study of Suzuki reactions which use nitrogen-containing heterocycles was described. This method was highly versatile (a single procedure was used for all substrates, including boronate esters and trifluoroborates), compatible with a variety of unprotected functionalities (e.g., NH2- and OH-substituted substrates), and efficient even with inactivated aryl chlorides.
Although many compounds look similar to this compound(847818-64-8)Related Products of 847818-64-8, numerous studies have shown that this compound(SMILES:CC(C)CN1N=CC=C1B(O)O), has unique advantages. If you want to know more about similar compounds, you can read my other articles.
Reference:
1,8-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N2 – PubChem