The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 4-Methyl-6-(methylthio)pyrimidin-2-ol( cas:16710-11-5 ) is researched.Application In Synthesis of 4-Methyl-6-(methylthio)pyrimidin-2-ol.Erkin, A. V.; Krutikov, V. I. published the article 《4-arylamino-2-(2-acetoxyethyl)amino-6-methylpyrimidines: Synthesis, deacetylation, and biological activity》 about this compound( cas:16710-11-5 ) in Russian Journal of General Chemistry. Keywords: ethanolamine acetate arylaminopyrimidinyl tuberculostatic preparation; pyrimidinediamine acetoxyethyl aryl tuberculostatic preparation; deacetylation acetoxyethylaminopyrimidine. Let’s learn more about this compound (cas:16710-11-5).
The reaction of 2-(2-acetoxyethyl)amino-4-chloro-6-methylpyrimidine with aromatic amines leads to a series of 4-arylamino-2-(2-acetoxyethyl)amino-6-methylpyrimidines. Deacetylation of these compounds proceeds in both acidic and basic media. Most of the (arylamino)pyrimidines obtained exhibit a pronounced antituberculous effect.
In some applications, this compound(16710-11-5)Application In Synthesis of 4-Methyl-6-(methylthio)pyrimidin-2-ol is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.
Reference:
1,8-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N2 – PubChem