HPLC of Formula: 91523-50-1. So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic. Compound: 6-Hydroxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid, is researched, Molecular C10H11NO3, CAS is 91523-50-1, about Synthesis and murine antineoplastic activity of bis[carbamoyloxymethyl] derivatives of pyrrolo[2,1-a]isoquinoline.
The title compounds I (R = Me2CH, cyclohexyl, R1 = MeO; R = Me, Et, cyclohexyl, R1 = H) were prepared I (R1 = MeO) were prepared from m-(PhCH2O)C6H4CHO via phenolic cyclization of m-HOC6H4CH2CH2NH2 with glyoxylic acid to give the isoquinoline II, which underwent cyclization with MeO2CCCCO2Me to give the pyrroloisoquinoline III. All I had P 388 lymphocytic activity. I (R = Me2CH, R1 = MeO) was tested in an expanded tumor panel and was shown to be active against B16 melanocarcinoma, CD8F1 mammary, L1210 lymphoid leukemia, colon 38, and MX-1 human tumor breast xenograft systems.
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Reference:
1,8-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N2 – PubChem