Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 91523-50-1, is researched, SMILESS is OC(=O)C1NCCC2=C1C=CC(O)=C2, Molecular C10H11NO3Journal, Asian Pacific Journal of Tropical Biomedicine called Gas chromatography mass spectrometry analysis and in vitro antibacterial activity of essential oil from Trigonella foenum-graecum, Author is Moniruzzaman; Shahinuzzaman; Haque, Ahsanul; Khatun, Rahima; Yaakob, Zahira, the main research direction is gas chromatog mass spectrometry antibacterial essential oil Trigonella.Safety of 6-Hydroxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid.
Objective: To evaluate the antibacterial activity of essential oil from Trigonella foenum-graecum seeds powder, and identify the compounds from the extracted oil. Methods: The seeds powder of Trigonella foenum-graecum was subjected to Clevenger extractor. Seven strains of bacteria were used to test antibacterial activity of the extract The activity against bacteria was tested by disk diffusion method using Whatman Number1 filter paper. Gas chromatog. mass spectrometry anal. was performed with an Agilent7890/5975B-gas chromatog./mass selective detector. Results: The hydrodistillation of seeds powder yielded 0.285% (v/w) of oil. Disk diffusion of the oil showed bactericidal activity against both Gram neg. and Gram pos. bacteria of lasted strains. The inhibition zone ranged from (8 ± 0) mm to (15.0 ± 0.7) mm depending on microbial strains. Gas chromatog. mass spectrometry anal. showed 14 different compounds The total compounds represented 80.96% of the oil. Conclusions: The antibacterial activity is due to the effects of different biol. active compounds present in the extract Identification of the compounds may help to develop new effective antimicrobial agent(s). Further researches on purification, characterization and toxicol. of the active compounds are needed.
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Reference:
1,8-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N2 – PubChem