Something interesting about 1569-17-1

This literature about this compound(1569-17-1)Recommanded Product: 4-Methyl-1,8-naphthyridinehas given us a lot of inspiration, and I hope that the research on this compound(4-Methyl-1,8-naphthyridine) can be further advanced. Maybe we can get more compounds in a similar way.

Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Yakugaku Zasshi called Catalytic dehalogenation reaction, Author is Miyaki, Takaaki; Kataoka, Eisei, which mentions a compound: 1569-17-1, SMILESS is CC1=C2C=CC=NC2=NC=C1, Molecular C9H8N2, Recommanded Product: 4-Methyl-1,8-naphthyridine.

Catalytic dehalogenation of 2,7-dichloro-4-methyl-1,8-naphthyridine with Pd-CaCO3 gave 4-methylnaphthyridine and chloro-4-methylnaphthyridine (the details to be reported later). Catalytic dehalogenation of 2,4-dichloro-6-methylpyrimidine gave a compound whose picrate (m. 130-1°) did not depress the m. p. of 6-methylpyrimidine picrate. In like manner the following compounds were studied with the reaction indicated: 4-phenyl-2,6-dichloropyrimidine → C10H8N2, m. 66-7°; 1-bromo-β-naphthol → β-naphthol; 1-bromo-β-naphthol Me ether → β-naphthol Me ether; bromopiperonal → piperonal; o-BrC6H4NO2 → aniline + o-bromoaniline + 2,2′-dibromoazoxybenzene.

This literature about this compound(1569-17-1)Recommanded Product: 4-Methyl-1,8-naphthyridinehas given us a lot of inspiration, and I hope that the research on this compound(4-Methyl-1,8-naphthyridine) can be further advanced. Maybe we can get more compounds in a similar way.

Reference:
1,8-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N2 – PubChem