In general, if the atoms that make up the ring contain heteroatoms, such rings become heterocycles, and organic compounds containing heterocycles are called heterocyclic compounds. An article called Design and cytotoxic evaluation of new annonaceous acetogenin analogues, published in 2007, which mentions a compound: 2689-65-8, Name is 5-Iodo-2-furaldehyde, Molecular C5H3IO2, Synthetic Route of C5H3IO2.
Analogs of annonaceous acetogenins were built up from 5-iodofuran-2-carbaldehyde and undec-10-ynoic acid or undec-10-yn-1-ol by a Sonogashira reaction, followed by a Grignard reaction and a Hg catalyzed hydratization. The cytotoxicity was evaluated with MTT assay (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide colorimetric assay for measuring cellular proliferation) against HL cells and at the National Cancer Institute (NCI) and found the activities only in the micromolar range.
There is still a lot of research devoted to this compound(SMILES：IC1=CC=C(O1)C=O)Synthetic Route of C5H3IO2, and with the development of science, more effects of this compound(2689-65-8) can be discovered.
Reference:
1,8-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N2 – PubChem