09/29/21 News What Kind of Chemistry Facts Are We Going to Learn About C18H16N2O2

Future efforts will undeniably focus on the diversification of the new catalytic transformations. In my other articles, you can also check out more blogs about 3491-12-1. Recommanded Product: 4-[4-(4-aminophenoxy)phenoxy]aniline.

You could be based in a university, combining chemical research with teaching; in a pharmaceutical company, working on developing and trialing new drugs; helping to ensure national healthcare provision keeps pace with new discoveries. , Recommanded Product: 4-[4-(4-aminophenoxy)phenoxy]aniline, 3491-12-1, Name is 4-[4-(4-aminophenoxy)phenoxy]aniline, molecular formula is C18H16N2O2, belongs to naphthyridine compound. In a document, author is Narender, Atmakuri, introduce the new discover.

2-Amino-pyridine-3-carboxaldehyde and 3-cyclopropyl-3-oxopropionic acid ethyl ester react each other to provide 2-cyclopropyl-[1,8]-naphthyridin-3-carboxylic acid ethylester (1) which reacts with 99 % hydrazine hydrate to yield 2-cyclopropyl-[1,8]-naphthyridine-3-carboxylic acid hydrazide (2). This acid hydrazide (2), reacts with different acetophenones to yield respective Schiff bases (3a-h). Compounds 3a-h react with Vilsmeier-Haack reagent (DMF/POCl3) to furnish 1-(2-cyclopropyl-[1,8]-naphthyridine-3-carbonyl)-3-phenyl-1H-pyrazole-4-carbaldehydes (4a-h). 2-Cyclopropyl-[1,8]-naphthyridine-3-carboxylic acid hydrazide (2) on reaction with substituted acetylacetones and substituted ethyl acetoacetates gives substituted 2-cyclopropyl-[1,8]-napthyridin-3-yl)-(3,5-dimethyl-pyrazol-1-yl)-methanones (5a-d) and 2-(2-cyclopropyl-[1,8]-naphthyridine-3-carbonyl)-5-methyl-2,4-dihydropyrazol-3-ones (6a-c), respectively. On the other hand, hydrazide (2) reacts with different aromatic aldehydes yields 2-cyclopropyl-[1,8]-naphthyridine-3-carboxylic acid benzylidene-hydrazides (7a-g). Compounds (7a-g) on reaction with mercapto-acetic acid offered 3-[(2-cyclopropyl-[1,8]-naphthyridin-3-yl-methyl)aminolphenyl-thiazolidin-4-ones (8a-g). Interaction of acid hydrazide (2) with different aromatic acid chlorides afford N’-acetyl/benzoyl-2-cyclopropyl-1,8-naphthyridine-3-carbohydrazides (9a-d), which on treatment with POCl3 yield 2-cyclopropyl-[1,8]-haphthytidin-3-yl)-(5-phenyl-[1,3,4]-oxadiazol-2-yl)methanone (10a-d).

Future efforts will undeniably focus on the diversification of the new catalytic transformations. In my other articles, you can also check out more blogs about 3491-12-1. Recommanded Product: 4-[4-(4-aminophenoxy)phenoxy]aniline.

Reference:
1,8-Naphthyridine – Wikipedia,
,1,8-Naphthyridine | C8H6N2 – PubChem