With the volume and accessibility of scientific research increasing across the world, Name: Adenosine 5′-monophosphate, it has never been more important to continue building the reputation for quality and ethical publishing we’ve spent the past two centuries establishing.61-19-8, Name is Adenosine 5′-monophosphate, SMILES is O[C@@H]([C@H]([C@H](N1C=NC2=C1N=CN=C2N)O3)O)[C@H]3COP(O)(O)=O, belongs to naphthyridine compound. In a article, author is Sporar, Joze, introduce new discover of the category.
A simple two-step synthesis of 1,6-naphthyridine derivatives is described. Methyl 2-(2-methoxy-2-oxoethyl)-6-oxo-1,6-dihydropyridine-3-carboxylate (3), prepared from dimethyl acetone-1,3-dicarboxylate (1) and propyolic acid amide (2) according to the known procedure, was transformed with N,N-dimethylformamide dimethyl acetal (DMFDMA) first into 2-[1-(dimethylamino)-3-methoxy-3-oxoprop-1-en-2-yl]-6-oxo-1,6-dihydropyridin e-3-dicarboxylate (4). This was followed by reaction with monosubstituted hydrazines 5a-h to afford substituted 1,6-naphthyridine-8-carboxylates 7a-h.
Future efforts will undeniably focus on the diversification of the new catalytic transformations. In my other articles, you can also check out more blogs about 61-19-8. Name: Adenosine 5′-monophosphate.
Reference:
1,8-Naphthyridine – Wikipedia,
,1,8-Naphthyridine | C8H6N2 – PubChem