The dynamic chemical diversity of the numerous elements, ions and molecules that constitute the basis of life provides wide challenges and opportunities for research. In an article, author is Powers, Ian G., once mentioned the application of 23814-12-2, Name is 1H-Benzo[d][1,2,3]triazole-5-carboxylic acid. Now introduce a scientific discovery about this category, Quality Control of 1H-Benzo[d][1,2,3]triazole-5-carboxylic acid.
C-H amination reactions are valuable transformations for the construction of C-N bonds. Due to their relatively high bond dissociation energies, C(sp(2))-H bonds are generally not susceptible toward direct nitrene insertion, necessitating alternative mechanisms for C-H activation. Here, we report that cationic dinuclear (NDI)Ni-2 (NDI = naphthyridine-diimine complexes catalyze intramolecular nitrene insertions into aryl and vinyl C(sp(2))-H bonds. Mechanistic studies suggest that a bridging imido ligand supported at a Ni-2 site induces C-H activation by a 1,2-addition pathway to generate an azametallacyclic intermediate. This organometallic mechanism contrasts with the electrocyclization/1,2-shift mechanism proposed for analogous transformations using Rh-2 catalysts. The implications of these mechanistic differences for the stereoselectivity and chemoselectivity of C-H amination are described.
These may comprise an expansion of the substrate scope from aromatic and heteroaromatic compounds to other hydrocarbons. If you like, you can also browse other articles about this kind. Thanks for taking the time to read the blog about 23814-12-2, Quality Control of 1H-Benzo[d][1,2,3]triazole-5-carboxylic acid.
Reference:
1,8-Naphthyridine – Wikipedia,
,1,8-Naphthyridine | C8H6N2 – PubChem