Chemical engineers work across a number of sectors, processes differ within each of these areas, but chemical engineering roles are found throughout, creation and manufacturing process of chemical products and materials. In an article, author is Wang, Chun-xia, once mentioned the application of 13922-41-3, Name is Naphthalen-1-ylboronic acid. Now introduce a scientific discovery about this category, Name: Naphthalen-1-ylboronic acid.
Fluorescent probes with the binding selectivity to specific structures in DNAs or RNAs have gained much attention as useful tools for the study of nucleic acid functions. Here, chloro-substituted 2-amino-5,7-dimethyl-1,8-naphthyridine (ClNaph) was developed as a strong and highly selective binder for target orphan cytosine opposite an abasic (AP) site in the DNA duplexes. ClNaph was then conjugated with thiazole orange (TO) via an alkyl spacer (ClNaph-TO) to design a light-up probe for the detection of cytosine-related mutations in target DNA. In addition, we found the useful binding and fluorescence signaling of the ClNaph-TO conjugate to target C in AP site-containing DNA/RNA hybrid duplexes with a view toward sequence analysis of microRNAs.
Future efforts will undeniably focus on the diversification of the new catalytic transformations. In my other articles, you can also check out more blogs about 13922-41-3. Name: Naphthalen-1-ylboronic acid.
Reference:
1,8-Naphthyridine – Wikipedia,
,1,8-Naphthyridine | C8H6N2 – PubChem