Chemical research careers are more diverse than they might first appear, as there are many different reasons to conduct research and many possible environments. , COA of Formula: https://www.ambeed.com/products/1118-61-2.html, 1118-61-2, Name is 3-Aminocrotononitrile, molecular formula is C4H6N2, belongs to naphthyridine compound. In a document, author is Ye, Pengqing, introduce the new discover.
We report herein a rare-earth-metal-catalyzed insertion of a 2-pyridine C(sp(2))-H bond into an intramolecular unactivated vinyl bond. This reaction provides streamlined access to a range of azaindolines in moderate to excellent yields. The salient features of this reaction include simple and mild reaction conditions, 100% atom efficiency, and wide substrate scope. This methodology is also used to construct other nitrogen-containing compounds such as naphthyridine derivatives. A plausible mechanism for the formation of azaindolines involving initial C-H bond activation by the lanthanide complex followed by C=C insertion into a Ln-C bond to form an alkyl lanthanide species that subsequently undergoes cyclization is proposed.
Future efforts will undeniably focus on the diversification of the new catalytic transformations. In my other articles, you can also check out more blogs about 1118-61-2. COA of Formula: https://www.ambeed.com/products/1118-61-2.html.
Reference:
1,8-Naphthyridine – Wikipedia,
,1,8-Naphthyridine | C8H6N2 – PubChem