Chemical Research Letters, May 2021. As an important bridge between the micro and macro material world, chemistry is one of the main methods and means for humans to understand and transform the material world. , Computed Properties of https://www.ambeed.com/products/99-09-2.html, 99-09-2, Name is 3-Nitroaniline, molecular formula is C6H6N2O2, belongs to naphthyridine compound. In a document, author is Takei, F., introduce the new discover.
A new fluorescence turn-on type of PCR monitoring system(Hpro-PCR) using a hairpin probe and a primer having a tag sequence at the 50 end with the fluorescent molecule 2,7-diamino-1,8-naphthyridine derivative (DANP) has been developed. The Hpro-PCR exploited the modulation of the equilibrium states between the DANP-bound hairpin structure and probe-tag duplex, and the PCR progress alternated the equilibrium state, resulting in the change of fluorescent intensity.
The potential utility of systematic synthetic strategy will be applicable to efficient generations of chemical libraries of compounds to find ‘hit’ molecules. I hope my blog about 99-09-2 is helpful to your research. Computed Properties of https://www.ambeed.com/products/99-09-2.html.
Reference:
1,8-Naphthyridine – Wikipedia,
,1,8-Naphthyridine | C8H6N2 – PubChem