New discoveries in chemical research and development in 2021. 553-97-9, Name is 2-Methylcyclohexa-2,5-diene-1,4-dione, molecular formula is C7H6O2, COA of Formula: https://www.ambeed.com/products/553-97-9.html, belongs to naphthyridine compound, is a common compound. In a patnet, author is Sun, Qi, once mentioned the new application about 553-97-9.
A 2,7-naphthyridine derivative (AND-OH) was used as a fluorophore in the development of a novel fluorescent turn-on probe (AND-DNBS) by introducing a 2,4-dinitrobenzenesulfonate functionality. This fluorescent probe was successfully used for sensing glutathione (GSH) in aqueous media and showed favorable properties such as a rapid response time (45 s) and a significant Stokes shift (227 nm). The characteristics of the developed probe are better than those of another probe, namely ND-DNBS, which was also synthesized by our group and most other previously reported fluorescent probes for GSH. The AND-DNBS probe was able to detect GSH via a red emission in living A549 cells and zebrafishes. These results show that AND-DNBS has potential applications as an excellent probe for detecting GSH in various environments.
Future efforts will undeniably focus on the diversification of the new catalytic transformations. In my other articles, you can also check out more blogs about 553-97-9. COA of Formula: https://www.ambeed.com/products/553-97-9.html.
Reference:
1,8-Naphthyridine – Wikipedia,
,1,8-Naphthyridine | C8H6N2 – PubChem