New Advances in Chemical Research in 2021. Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. 149022-15-1, Name is 3-Methyl-2-benzothiazolinone hydrazone hydrochloride hydrate(1:1:x), molecular formula is , belongs to naphthyridine compound. In a document, author is Balkenhohl, Moritz, Safety of 3-Methyl-2-benzothiazolinone hydrazone hydrochloride hydrate(1:1:x).
A set of successive regioselective metalations and functionalizations of the 1,5-naphthyridine scaffold are described. A combination of Zn-, Mg-, and Li-TMP (TMP = 2,2,6,6-tetramethylpiperidyl) bases and the presence or absence of a Lewis acid (BF3 center dot OEt2) allows the introduction of up to three substituents to the 1,5-naphthyridine core. Also, a novel halogen dance reaction was discovered upon metalation of an 8-iodo-2,4-trifunctionalized 1,5-naphthyridine allowing a fourth regioselective functionalization. Additionally, reactions leading to key 1,5-naphthyridines for the preparation of OLED materials and a potential antibacterial agent were performed.
These may comprise an expansion of the substrate scope from aromatic and heteroaromatic compounds to other hydrocarbons. If you like, you can also browse other articles about this kind. Thanks for taking the time to read the blog about 149022-15-1, Safety of 3-Methyl-2-benzothiazolinone hydrazone hydrochloride hydrate(1:1:x).
Reference:
1,8-Naphthyridine – Wikipedia,
,1,8-Naphthyridine | C8H6N2 – PubChem