New Advances in Chemical Research, April 2021.The transformation of simple hydrocarbons into more complex and valuable products via catalytic C–H bond functionalisation has revolutionised modern synthetic chemistry. 40138-16-7, Name is (2-Formylphenyl)boronic acid, SMILES is O=CC1=CC=CC=C1B(O)O, belongs to naphthyridine compound. In a document, author is Srivastava, Sanjay K., introduce the new discover, SDS of cas: 40138-16-7.
Several 1,8-naphthyridine-3-carboxamide derivatives (8 – 23) were synthesized and tested for in vitro cytotoxicity against eight cancer cell lines and a normal cell line. Compound 12 exhibited high cytotoxicity (IC50=1.37 mu M) in HBL-100 ( breast) cell line while compounds 17 (IC50=3.7 mu M) and 22 (IC50=3.0 mu M) have shown high cytotoxicity in KB (oral) and SW-620 (colon) cell lines, respectively. The synthesized 1,8-naphthyridine-3-carboxamides were also evaluated for anti-inflammatory and myeloprotective activities, indicated by modulation in cytokine and chemokine levels secreted by dendritic cells. (c) 2007 Published by Elsevier Ltd.
Therefore, this conceptually novel strategy might open impressive avenues to establish green and sustainable chemistry platforms. If you like, you can also browse other articles about this kind. Thanks for taking the time to read the blog about 40138-16-7, SDS of cas: 40138-16-7.
Reference:
1,8-Naphthyridine – Wikipedia,
,1,8-Naphthyridine | C8H6N2 – PubChem